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People with ovarian cancer frequently receive aggressive end-of-life care despite industry guidelines that emphasize quality of life for those with advanced disease, according to a recent study. In fact, by 2016, ICU stays and emergency department visits in the last month of life had become more common for people with ovarian cancer than they were […]
As researchers and medical professionals work to develop new treatments for cancer, they face a variety of challenges. One is intratumor heterogeneity—the presence of multiple kinds of cancer cells within the same tumor. Often, these “mosaic” tumors include cells, such as polyploidal giant cancer cells, that have evolved to become aggressive and resistant to chemotherapy […]
When the heart suddenly can’t pump enough blood to meet the body’s needs after a heart attack, women ages 18-55 get less aggressive care in the hospital and are more likely to die prior to discharge than men the same age, according to new research published today in Circulation: Heart Failure, an American Heart Association […]
Researchers from Regenstrief Institute and Indiana University report that nearly half of the time medical treatments and orders received for incapacitated patients were not compatible with goals of care requested by their surrogate decision makers. The most common disagreement involved a “full-code” medical order prepared for patients whose surrogates had indicated preference for less aggressive […]
Researchers at the University of Maryland School of Medicine (UMSOM) developed a new nanoparticle drug formulation that targets a specific receptor on cancer cells, and appears to be more effective than a standard nanoparticle therapy currently on the market to treat metastatic breast cancer. The study, published today in the journal Science Advances, found that […]
Peter Mac scientists have found a way to target acute myeloid leukemia (AML) at its source—a discovery that could yield a more effective treatment for this aggressive and often incurable blood cancer. Prof Mark Dawson and Dr. Laura MacPherson led the international research team, in collaboration with researchers in Europe and Australia including at the […]
Despite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of patients achieving five-year survival remains low, according to new Mayo Clinic research. A study to be published next month in Mayo Clinic Proceedings finds that little has changed in terms of five-year survival—only […]
Cervical cancer negative for the human papilloma virus (HPV) is rare but more aggressive. It is more frequently diagnosed at advanced stages, with more metastasis and reduced survival. These are the conclusions of a study co-led by ISGlobal, an institution supported by “la Caixa,” the Hospital Clinic and the University of Barcelona. Cervical cancer is […]
UCSF Benioff Children’s Hospitals are harnessing next-generation genomic technology to develop individualized drug cocktails in a new trial for children with a type of malignant brain tumor. This precision-medicine approach offers a new strategy in the treatment for high-grade glioma, an intractable brain cancer in which survival has plateaued for decades. In the trial, UCSF […]
Glioblastoma is a highly aggressive brain cancer that predominantly affects people in their 50s, 60s and 70s. Even under the best available care, half of the patients die within one year after diagnosis, and very few live on for more than three years. Many efforts to develop new, targeted treatments have failed over the last […]