Health News

Regulating copper in the brain stops memory loss in a mouse model of Alzheimer’s

Alzheimer’s disease is characterized by the presence of amyloid plaques in the patient’s brain. These plaques sequester copper, and contain approximately five times as much as a healthy brain. Two CNRS scientists from the Coordination Chemistry Laboratory recently developed, with their colleagues from the Guangdong University of Technology and Shenzhen University (China), a molecule that […]

Health News

Potential new therapies for Alzheimer’s are revealed through network modeling of its complex molecular interactions

Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer’s Disease (LOAD), as well as a promising therapeutic candidate for treatment, according to a study in the journal Neuron. LOAD is the most prevalent form of dementia among people over age 65, a […]

Health News

Novel compound is promising drug candidate for Alzheimer’s disease

A newly identified compound is a promising candidate for inhibiting the production of amyloids, the abnormal proteins that form toxic clumps, called fibrils, inside the brains of patients with Alzheimer’s disease. As published today in the Royal Society of Chemistry’s Chemical Communications, the compound—known as “C1″—uses a novel mechanism to efficiently prevent the enzyme gamma-secretase […]

Health Problems

Exploring how lipids and cholesterol relate to Alzheimer’s

Professor Jing Xu and her students study extremely tiny motor proteins, but their work could make a huge contribution to the growing body of knowledge about Alzheimer’s and other diseases that progressively destroy brain tissue. Alzheimer’s disease is, so far, untreatable and incurable and is the sixth most common cause of death in adults in […]