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People who have a gene variant associated with an increased risk of developing Alzheimer’s disease also tend to have changes in the fluid around their brain and spinal cord that are detectable years before symptoms arise, according to new research from Duke Health. The work found that in people who carry the APOE4 gene variant, […]
Alzheimer’s disease is characterized by the presence of amyloid plaques in the patient’s brain. These plaques sequester copper, and contain approximately five times as much as a healthy brain. Two CNRS scientists from the Coordination Chemistry Laboratory recently developed, with their colleagues from the Guangdong University of Technology and Shenzhen University (China), a molecule that […]
Researchers from Mount Sinai and the National Center for Geriatrics and Gerontology in Japan have identified new molecular mechanisms driving late-onset Alzheimer’s Disease (LOAD), as well as a promising therapeutic candidate for treatment, according to a study in the journal Neuron. LOAD is the most prevalent form of dementia among people over age 65, a […]
Researchers at the Universitat Autònoma de Barcelona (UAB) have conducted a study which allows estimating the effects of isolation in the current pandemic scenarios in elderly patients with dementia. The findings could serve as a guide to the rethinking of these conditions after the COVID-19 crisis. The study was published in a special edition of […]
Dementia is the name given to a group of symptoms linked to an ongoing decline in brain function. You could lower your risk of the neurodegenerative condition by simply steaming your vegetables, it’s been claimed. There are a number of different types of dementia, and the most common in the UK is Alzheimer’s disease. Diagnosing […]
Alzheimer’s disease: use of a cancer drug? Alzheimer’s dementia is the most common age-related neurodegenerative disease. Curable it is not yet. However, due to certain medicines, symptoms and concomitants the disease can be alleviated. A cancer drug could be used. In spite of the great increase of Knowledge of recent years and the development of […]
The death of a spouse often means the loss of intimacy, companionship and everyday support for older adults. A new study finds that widowhood can have another profound effect: It may accelerate cognitive decline. Investigators from Brigham and Women’s Hospital and Massachusetts General Hospital analyzed older, cognitively normal Americans enrolled in the Harvard Aging Brain […]
For over a century, Alzheimer’s disease has confounded all attempts to treat it. But in recent years, perplexing experiments using flickering light have shown promise. Now, researchers have tapped into how the flicker may work. They discovered in the lab that the exposure to light pulsing at 40 hertz—40 beats per second—causes brains to release […]
A newly identified compound is a promising candidate for inhibiting the production of amyloids, the abnormal proteins that form toxic clumps, called fibrils, inside the brains of patients with Alzheimer’s disease. As published today in the Royal Society of Chemistry’s Chemical Communications, the compound—known as “C1″—uses a novel mechanism to efficiently prevent the enzyme gamma-secretase […]
Professor Jing Xu and her students study extremely tiny motor proteins, but their work could make a huge contribution to the growing body of knowledge about Alzheimer’s and other diseases that progressively destroy brain tissue. Alzheimer’s disease is, so far, untreatable and incurable and is the sixth most common cause of death in adults in […]