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About 50 percent of people who reach the age of 85 will develop Alzheimer’s disease. Most will die within about five years of exhibiting the hallmark symptoms of the disease – severe memory loss and a precipitous decline in cognitive function. But the molecular processes that lead to the disease will have begun years earlier. […]
THURSDAY, July 26 — There have been many setbacks on the long road to finding a treatment that might slow or stop Alzheimer’s disease, but a new trial offers a glimmer of hope. Researchers report that an experimental drug called BAN2401 slowed mental decline by as much as 30 percent in Alzheimer’s patients. It also […]
(HealthDay)—There have been many setbacks on the long road to finding a treatment that might slow or stop Alzheimer’s disease, but a new trial offers a glimmer of hope. Researchers report that an experimental drug called BAN2401 slowed mental decline by as much as 30 percent in Alzheimer’s patients. It also appeared to clear away […]
The MODEL-AD Center, an ambitious project to develop and distribute precise mouse models of late-onset Alzheimer’s disease (AD), has released eight new models carrying genetic mutations found in patients. In past decades, most AD researchers had to rely on mouse models that carried a genetic mutation associated with the relatively rare, early-onset, familial version of […]
A new, highly accurate MRI technique can monitor iron levels in the brains of multiple sclerosis (MS) patients and help identify those at a higher risk for developing physical disability, according to a study published in the journal Radiology. MS is a disease that attacks three critical components of the central nervous system: the neurons […]
Scientists have discovered a “Big Bang” of Alzheimer’s disease – the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain. A study from UT Southwestern’s O’Donnell Brain Institute provides novel insight into the shape-shifting nature of a tau molecule just before it begins sticking to […]
Researchers at Indiana University have found early evidence that tiny snippets of genetic material called microRNA may help with early detection of conditions such as Alzheimer’s disease. The study, published June 18 in Scientific Reports, found that changes in microRNA are detectable in mice long before they start to show symptoms from neurodegeneration. These microRNA […]