Orthodontic relapse is fairly common; however, the mechanisms between relapse and the dental arch form remain unclear. The purpose of the study described in a new article in the BIO Integration journal was to establish three-dimensional (3D) finite element models of different dental arch forms after orthodontic treatment and to analyze the states of different […]
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In-depth analysis identifies causes and mitigation efforts in COVID-19 cluster
Hospitals across the United States have gone to great lengths to implement infection control measures to prevent transmission of SARS-CoV-2. And yet, as the pandemic has unfolded, many health care settings have experienced clusters of cases, with the virus spreading among patients, staff or both. Some clusters have been easily traced back to break rooms […]
Immune marker analysis: Size of tumor tissue area crucial for survival prognosis
The method of choice used for preparing tissue samples can lead to biased results in the analysis of cancer patient survival. For microscopical analysis, full tissue samples provide a better picture of the immune cell activity in the tumor compared to tissue-sparing punch biopsies. A team led by the visceral surgeon Elisabeth S. Gruber and […]
Whole-genome sequencing analysis to find more exact biomarkers
A new study from Uppsala University shows that whole-genome sequencing increases the precision of genetic studies, which in turn can improve our understanding of how to use biomarkers to discover disease. The results are published in the scientific journal Scientific Reports. Biomarkers, such as specific proteins circulating in our blood stream, are often used in […]
Scientists develop method to standardize genetic data analysis
MIPT researchers have collaborated with Atlas Biomedical Holding and developed a new bioinformatics data analysis method. The developed program, EphaGen, can be used for quality control when diagnosing genetic diseases. The team published the article in Nucleic Acid Research. The mapping of the human genome in the early 21st century and understanding the nucleic acid […]
When is best time to get flu shot? Analysis compares scenarios
When flu season peaks after mid-winter, tens of thousands of influenza cases and hundreds of deaths can likely be avoided if older adults wait until October to get their flu immunization, a University of Pittsburgh School of Medicine analysis reveals in the April issue of the American Journal of Preventive Medicine. The protection offered by […]
Epigenetic analysis of aggressive brain tumors
Glioblastoma is a highly aggressive brain cancer that predominantly affects people in their 50s, 60s and 70s. Even under the best available care, half of the patients die within one year after diagnosis, and very few live on for more than three years. Many efforts to develop new, targeted treatments have failed over the last […]
Analysis of prostate tumors reveals clues to cancer’s aggressiveness
Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common. The study lays the foundation for finding new ways to treat prostate cancer, particularly for the most aggressive forms of the disease. The multicenter study, which examined the […]