The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction and chronic infections. To explore the cellular and molecular mechanisms underlying the role of NKCC1 in the intestinal pathology, Eric Delpire, Ph.D., and […]
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Blood-brain barrier damage occurs even with mild head trauma
In a new study of adolescent and adult athletes, researchers at Ben-Gurion University of the Negev, Stanford University and Trinity College in Dublin have found evidence of damage to the brain’s protective barrier, without a reported concussion. For the first time, the researchers were able to detect damage to the blood-brain barrier (BBB), which protects […]