What makes us human, and where does this mysterious property of “humanness” come from? Humans are genetically similar to chimpanzees and bonobos, yet there exist obvious behavioral and cognitive differences. Now, researchers from the Salk Institute, in collaboration with researchers from the anthropology department at UC San Diego, have developed a strategy to more easily […]
A better way to measure cell survival: New test rapidly evaluates the effect of drugs and potentially toxic compounds on cells
Measuring the toxic effects of chemical compounds on different types of cells is critical for developing cancer drugs, which must be able to kill their target cells. Analyzing cell survival is also an important task in fields such as environmental regulation, to test industrial and agricultural chemicals for possible harmful effects on healthy cells. MIT […]
Measuring stress around cells: Findings offer clues as to how cells act collectively to shape tissues and organs
Tissues and organs in the human body are shaped through forces generated by cells, that push and pull, to “sculpt” biological structures. Thanks to a new tool developed at McGill University, scientists will now be able to watch, and map these forces. Christopher Moraes, an assistant professor in McGill’s Department of Chemical Engineering, and colleagues […]
A new way to transfer energy between cells
Researchers from the Catalonian Institute of Bioengineering (Instituto de Bioingeniería de Cataluña) and the Seville Chemical Research Institute (Instituto de Investigaciones Químicas de Sevilla) have described a new method for the transmission of electrons between proteins that refutes the evidence from experiments until now. This process, involved in the generation of energy in both animal […]
How much are we learning about the genome? Natural selection is science’s best critic
In 2003, the Human Genome Project revealed to the world the three billion chemical units within human DNA. Since that time, scientists have designed many ways to organize and assess this overwhelmingly large amount of information. Now, scientists at Cold Spring Harbor Laboratory (CSHL) have determined that evolution can help guide these efforts. Researchers have […]
A Trojan horse delivery method for miRNA-enriched extracellular vesicles
A method for large-scale production of extracellular vesicles enriched with specific microRNAs (miRNAs) has been developed in the Wake Forest Institute for Regenerative Medicine (WFIRM) labs, offering a manufacturing standardization process which may have therapeutic applications and clinical impact. Extracellular vesicles are currently of particular interest in the scientific community for their therapeutic potential as […]
New insight into the evolution of the nervous system
Pioneering research has given a fascinating fresh insight into how animal nervous systems evolved from simple structures to become the complex network transmitting signals between different parts of the body. The new study used simple multicellular organisms called Placozoa to reveal the beginnings of the nervous systems found in more complex animals. The international research […]
How fatal biofilms form
By severely curtailing the effects of antibiotics, the formation of organized communities of bacterial cells known as biofilms can be deadly during surgeries and in urinary tract infections. Yale researchers have just come a lot closer to understanding how these biofilms develop, and potentially how to stop them. Biofilms form when bacterial cells gather and […]
The immune system of the alpaca reveals a potential treatment for cancer
The natural world often provides the answer to unsolved medical problems. On this occasion, the solution to a challenge posed by cancer has come about from the immune system of camelids. A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and the Vrije Universiteit Brussel (VUB), in Belgium, describes a number of […]
Particles surf their own waves, reveal how microbes and cells move through human body
Surf’s up for microbes swimming beside red blood cells. New calculations and experiments model for the first time how spherical particles submerged in gooey liquid travel along a flexible rubber sheet; comparable conditions are common in the human body, such as blood cells flowing through a capillary or the journeys of self-propelled microbes. (Although blood […]