Health News

ACE Inhibitor Prevents LVEF Decline After Breast Cancer Drugs

For women with HER2-positive early breast cancer treated with an anthracycline-based regimen followed by trastuzumab (Herceptin), concurrent therapy with the angiotensin-converting enzyme (ACE) inhibitor lisinopril can help to prevent a decline in left-ventricular ejection fraction (LVEF) below 50%, investigators in a community-based study found. Among 424 women with HER2-positive early-stage breast cancer, the rate of […]

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FDA Panel Backs Atezolizumab for mTNBC — at Least for Now

On the first day of a historic three-day meeting into cancer indications that were granted an accelerated approval by the Food and Drug Administration (FDA), the first one to come under discussion is staying in place, at least for now. Members of the FDA’s Oncologic Drugs Advisory Committee (ODAC) voted 7-2 in favor of keeping […]

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Tumorsphere Formulation and Use in Cancer Stem Cell Research

Skip to: What are tumorspheres? Tumorsphere formation assay Technical notes on tumorsphere cultivation What are the types of cancer stem cell (CSC) tumorspheres? Tumorspheres for screening anti-CSC drugs What is the future of tumorspheres? What are tumorspheres? Numerous studies have pointed out that cancer stem cells (CSCs) play an important role in cancer progression, metastasis, […]

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Oral hormone therapy shown to significantly alter metabolome of menopausal women

Groundbreaking research led by a team of scientists including a University of Massachusetts Amherst biostatistician shows that oral hormone therapy (HT) significantly alters the metabolome of postmenopausal women. This finding, which examined blood specimens from the landmark Women’s Health Initiative (WHI) study, may help explain the disease risks and protective effects associated with different regimens […]