Statin use among patients with heart failure is associated with a 16% lower risk of developing cancer compared with non-statin users during an average of four years of follow-up, according to new research published today (Wednesday) in the European Heart Journal. In addition, the study found that statin use was associated with a 26% reduced […]
Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells
Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails. Understanding this 'choice' by the cancer cells may help us devise better therapeutic strategies. Now, the team of Prof. Jean-Christophe Marine (VIB-KU Leuven Center for Cancer Biology) shows […]
Cancer a compelling reason to cut alcohol, and drink counting helps
A new study comparing different ways of encouraging people to reduce their alcohol intake has found telling people alcohol causes cancer makes them want to drink less, and encouraging them to count their drinks helps them do it. Lead author Professor Simone Pettigrew from The George Institute for Global Health said that harmful alcohol use […]
Study reveals prevalence of multimorbidity among people using methamphetamine
People who use methamphetamine are more likely to have health conditions, mental illness, and substance use disorders than people who do not use the drug, according to a new study by researchers at the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU School of Global Public Health. The findings are published in the […]
Groundbreaking study optimizes patient's own immune system to fight tumors
A groundbreaking study led by engineering and medical researchers at the University of Minnesota Twin Cities shows how engineered immune cells used in new cancer therapies can overcome physical barriers to allow a patient's own immune system to fight tumors. The research could improve cancer therapies in the future for millions of people worldwide. The […]
Machine learning technique detects epigenetic drivers of cancers
Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease. Now a team led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center (NYGC) has developed a machine learning technique for detecting other modifications to DNA that have a similar […]
Study: Stereotactic body radiotherapy can be safely used to treat patients with multiple metastases
The first National Institutes of Health (NIH) National Cancer Institute (NCI)-funded clinical study examining stereotactic body radiotherapy (SBRT) in the treatment of oligometastatic breast, prostate, and non-small cell lung (NSCLC) cancers displayed evidence that SBRT can be safely used to treat patients who have multiple metastases. These results were recently published in JAMA Oncology. The […]
FDA approves immunotherapy for treating patients with dMMR endometrial cancer
Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA […]
Personalized cancer vaccines for breast, pancreatic cancers show promise
The COVID-19 vaccines — designed using bits of genetic information that prime our immune systems to recognize and fight off viral infections — have become lifesavers in the global fight to end the pandemic. Now, new research from Washington University School of Medicine in St. Louis has shown that a similar vaccine approach can be […]
NLR May Be Tied to Survival in Patients With NSCLC Brain Metastases
NEW YORK (Reuters Health) – In patients with non-small cell lung cancer brain metastases (NSCLCBM) treated with immune-checkpoint inhibitors (ICIs) and upfront steroids, a low neutrophil-to-lymphocyte ratio (NLR) was associated with lower overall survival in a single-center retrospective analysis. “With widespread implementation of ICIs for treatment of NSCLC, many clinicians have concerns that the immunosuppressive […]