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The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes. Tested on isolated human and mouse pancreatic islets, mouse and rat cell cultures and animal models of both Type 1 and Type 2 diabetes, the experimental drug significantly improved four […]
A newly identified compound is a promising candidate for inhibiting the production of amyloids, the abnormal proteins that form toxic clumps, called fibrils, inside the brains of patients with Alzheimer’s disease. As published today in the Royal Society of Chemistry’s Chemical Communications, the compound—known as “C1″—uses a novel mechanism to efficiently prevent the enzyme gamma-secretase […]
A single dose of a highly diluted VSV-Ebola virus (EBOV) vaccine—approximately one-millionth of what is in the vaccine being used to help control the ongoing Ebola outbreak in the Democratic Republic of the Congo (DRC)—remains fully protective against disease in experimentally infected monkeys, according to National Institutes of Health scientists. The NIH investigators completed the […]