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The pandemic of coronavirus disease 2019 (COVID-19), declared to be such in March 2020 by the World Health Organization (WHO), is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Seemingly unpredictable in the intensity of consequent illness, and with a terrifying capacity to spread both rapidly and extensively during asymptomatic infection – or […]
A new study led by Hans-Martin Jäck of the Friedrich-Alexander University Erlangen-Nuremberg in Germany engineered clusters of neutralizing monoclonal antibodies using a transgenic mouse model. A unique characteristic for the antibodies was the different ways it bound to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the overall reduction in the viral spread for […]
The alarmingly high infection rate of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus 2019 (COVID-19) pandemic, has had an enormous impact on healthcare in many parts of the world. The surge in the rate of hospitalization, especially intensive care unit admissions, has placed an overwhelming burden on healthcare systems […]
When a virus invades an individual, both innate and adaptive immunity play crucial roles. The successful viral pathogens can antagonize these immune pathways with genes that inhibit the key players in the immune system. The coronavirus disease 2019 (COVID-19) pandemic is caused by the novel beta coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It […]
In a recent report posted to the bioRxiv* preprint server, researchers from the United Kingdom and Uganda reveal unique protein features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relative to other representatives of Sarbecoviruses. The causative agent of the coronavirus disease 2019 (COVID-19), SARS-CoV-2, belongs to the Betacoronavirus genus and Sarbecovirus subgenus of the […]
There have been concerns that several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have mutations that allow them to evade the immune system. A new study published in the Open Forum Infectious Diseases suggests otherwise. Led by Aaron AR Tobian of Johns Hopkins University School of Medicine, results showed that except for one from […]
The novel beta-coronavirus virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and coronaviruses, in general, alter the host's cellular metabolism to support massive production of ~30 kB viral genomes and subgenomic viral RNAs. However, how this is achieved is largely unknown. Researchers from Brigham and Women's Hospital, Massachusetts General Hospital (MGH), and the Broad Institute […]
Exposure to particulate matter — a mixture of liquid and solid particles suspended in the air that ranges from dust to airborne transmission of viral droplets — has been harmful to human health. Research led by Maria de Fatima Andrade from the University of São Paulo in Brazil found particulate matter plays a significant role […]
The coronavirus disease 2019 (COVID-19) pandemic has taken a heavy toll on human lives, with over two million casualties so far. Equally devastating has been its economic toll. Now, a new study, which was released on the medRxiv* preprint server, describes the features and frequency of long-haul symptoms in COVID-19. Study: Population-based estimates of post-acute […]
In a recent report made available on bioRxiv* preprint server, researchers from Poland and Finland reveal a spillover event of mink-adapted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from farmed mink to humans after an extensive adaptation process. Study: Zoonotic spillover of SARS-CoV-2: mink-adapted virus in humans. Image Credit: An inspiration / Shutterstock Even before […]