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Researchers explore how N501Y mutation in SARS-CoV-2 increases viral transmissibility

Researchers at Erasmus University Medical Center in The Netherlands have explored how and why new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), have exhibited heightened infectivity. Study: Experimental evidence for enhanced receptor binding by rapidly spreading SARS-CoV-2 variants. Image Credit: Design_Cells / Shutterstock They suggest […]

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Why Are Vaccines Still in Short Supply?

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Boxes containing the Pfizer-BioNTech covid-19 vaccine are prepared to be shipped at the Pfizer Global Supply Kalamazoo manufacturing plant. The U.S. government has invested billions of dollars in manufacturing, used a wartime act dozens of times to boost supplies and yet […]

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Afghanistan begins COVID-19 vaccination drive amid rising violence

KABUL (Reuters) – Afghanistan began its first COVID-19 vaccinations on Tuesday, administering doses initially to security force members, health workers and journalists, in a campaign that may face challenges from a sharp rise in violence.Slideshow ( 3 images )The war-damaged country received 500,000 doses of AstraZeneca’s vaccine from the Serum Institute of India (SII), which […]

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Trials of retooled vaccines for variants could take months: U.S. FDA

(Reuters) – Drugmakers should test any COVID-19 vaccines that have been retooled to combat new variants of the coronavirus in clinical trials designed to track the immune response of hundreds of test subjects, which could take months, U.S. regulators said on Monday.Slideshow ( 3 images )Vaccine developers may need to modify their shots to provide […]

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Psychiatrists’ Happiness, Well-Being Hit Hard by COVID-19

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Events of the past year have taken a huge toll on the happiness, wellness, and lifestyles of many, but especially those in the healthcare field, including psychiatrists. The newly released Medscape Psychiatrist Lifestyle, Happiness & Burnout Report 2021 reveals how psychiatrists […]

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The origin of SARS-CoV-2 furin cleavage site remains a mystery

The ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has largely defied attempts to contain its spread by non-pharmaceutical interventions (NPIs). With the massive loss of life and economic damage, the only way out, in the absence of specific antiviral therapeutics, has been the development of […]