Americans remain hopeful for coronavirus vaccine following the Thanksgiving holiday Internal medicine physician Dr. Shoshana Ungerleider calls recent vaccine developments ‘truly incredible.’ An anti-inflammatory drug widely used to treat gout and other conditions is the latest to be added to a large-scale trial in the U.K. that is investigating potential treatments for coronavirus. Researchers leading […]
Age is decisive for positive or negative effects of the diabetes drug metformin
Metformin is a common type 2 diabetes drug. Recently, it was found to extend life span of young non-diabetic animals but the responses of older organisms to metformin remain unexplored. Researchers at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena, Germany, and the Friedrich Schiller University Jena found that mitochondrial dysfunction abrogates metformin […]
Newer Rheumatoid Arthritis Drug May Help Ease Tough-to-Treat Cases
MONDAY, Oct. 19, 2020 — A recently approved rheumatoid arthritis medication appears to be an effective second-line therapy when biologic treatments start to fail, a new clinical trial reports. Arthritis sufferers treated with upadacitinib had a significantly greater reduction in their symptoms and disease activity than people treated with a standard disease-modifying antirheumatic drug (DMARD), […]
Virus-mimicking drug helps immune system target cunning cancer cells
Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that a drug that activates the body’s natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy. The findings, published today in the journal Science Translational Medicine, open […]
India gets affordable drug to treat pulmonary fibrosis, Glenmark Pharma launches generic version of Nintedanib
Glenmark Pharma on Wednesday announced the launch of its generic version of Nintedanib (NINDANIB), used for the treatment of pulmonary fibrosis, in India. “Glenmark being a leader in the area of respiratory has been amongst the first to launch the branded generic version at an affordable cost for the treatment of pulmonary fibrosis in India,” […]
These genes help explain how malaria parasites survive treatment with common drug
The essential malaria drug artemisinin acts like a “ticking time bomb” in parasite cells—but in the half a century since the drug was introduced, malaria-causing parasites have slowly grown less and less susceptible to the treatment, threatening attempts at global control over the disease. In a paper published September 23 in Nature Communications, Whitehead Institute […]
Targeted drug for lung cancer approved for NHS use in England
In two decisions published today, the National Institute for Health and Care Excellence (NICE) has approved the drug osimertinib (Tagrisso) to treat some adults in England with advanced lung cancer whose cancer tests positive for a faulty version of a molecule called EGFR. Around 1,800 people in England have advanced EGFR-positive lung cancer, and the […]
Two bereaved mothers share a shattering warning after an acne drug
‘We can’t get our daughters back, but we can warn others about this acne drug’: As prescriptions for a common skin treatment soar, two bereaved mothers share a shattering warning Annabel Wright, 15, killed herself in her family home in North Yorkshire last year Parents say she was overwhelmed by suicidal feelings brought on by […]
Novel diabetes drug candidate shows promising properties in human islets and mouse models
The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes. Tested on isolated human and mouse pancreatic islets, mouse and rat cell cultures and animal models of both Type 1 and Type 2 diabetes, the experimental drug significantly improved four […]
Experimental drug shows early promise against inherited form of ALS, trial indicates
An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine in St. Louis, Massachusetts General Hospital in Boston and other sites around the world and sponsored by the pharmaceutical company Biogen Inc. The trial indicated […]