As the fast-moving Ebola virus sweeps through eastern Congo, scientists are braving war zones hoping to test new medicines on sick patients there. Despite civil unrest in the region, Doctors Without Borders has set up testing sites in the cities of Butembo and Beni, the latest hot spots of the current Ebola outbreak in the […]
New tuberculosis drug may shorten treatment time for patients
A new experimental antibiotic for tuberculosis has been shown to be more effective against TB than isoniazid, a decades-old drug which is currently one of the standard treatments. In mouse studies, the new drug showed a much lower tendency to develop resistance, and it remains in the tissues where the Mycobacterium tuberculosis bacteria reside for […]
Women’s hormones play role in drug addiction, higher relapse rates
Women’s hormonal cycles may not only make them more prone to drug addiction but also more affected by triggers that lead to relapse, a new Vanderbilt University study revealed. The findings are especially significant since there are virtually no addiction studies in women that account for these cycles. Erin Calipari, an assistant professor of pharmacology […]
New drug brings unexpected hope in targeting cancer cells
An unexpected finding in pre-clinical platelet studies by Baker Institute researchers could provide a novel approach to targeting and destroying difficult-to-treat cancer cells, providing new therapeutic options for a range of cancers. This latest finding, published in the journal Theranostics, was discovered while studying activated platelets in the setting of heart disease and may now […]
Simple drug combination creates new neurons from neighboring cells
A simple drug cocktail that converts cells neighboring damaged neurons into functional new neurons could potentially be used to treat stroke, Alzheimer’s disease, and brain injuries. A team of researchers at Penn State identified a set of four, or even three, molecules that could convert glial cells—which normally provide support and insulation for neurons—into new […]
Drug that clears out dead cells left mice more active
Could this be the fountain of youth? Drug that clears out dead cells left mice more active with lower levels of inflammation Researchers at the Weizmann Institute of Science in Israel investigated how the immune system clears away ageing cells These cells are not completely dead but are irreparably damaged They administered a drug that […]
Dose Optimization: What To Do When Your Insurer Doesn’t Cover Your Drug Dosage
What is dose optimization? Dose optimization, like other coverage restrictions, is a way for insurance companies to cut costs. If your prescription is written for several pills per day and the medication comes in a strength that has the same daily dose in one pill, your insurer may require you to get the […]
FDA Warns of Rare Stroke Risk With Multiple Sclerosis Drug
WEDNESDAY, Dec. 5, 2018 — A new warning has been added to the multiple sclerosis drug Lemtrada (alemtuzumab) after rare reports of patients suffering strokes and tears in the lining of the arteries in the head and neck, the U.S. Food and Drug Administration said. Most patients with these issues developed symptoms within a day […]
Shortcut strategy for screening compounds with clinical potentials for drug development
Developing a new drug often takes years and costs hundreds of millions of dollars. A shortcut has now been reported in a study led by City University of Hong Kong (CityU), which can potentially reduce the time and costs of developing new drugs by sorting out the high potential candidates from a long list of […]
Drug treatment could offer new hope for some patients with brain bleeding
A drug treatment, already approved for use in patients, could offer new hope for some patients with brain bleeding and strokes. New research, led by the University of Glasgow and published today in Human Molecular Genetics, has shown that the compound sodium phenyl butyric acid could be used to reduce brain bleeding which can cause […]