The protein titin is a large structural component of the sarcomere—the machinery that mediates contraction of cardiac muscle cells. Despite its importance to the beating heart, little is known about titin turnover. Adrian Cadar, Ph.D., and colleagues have now used the microscopy technique FRAP (fluorescence recovery after photobleaching) to study titin dynamics in contracting cardiomyocytes. […]
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Ebola in Uganda, and the dynamics of a new and different outbreak
The 2018 Ebola outbreak in the Democratic Republic of Congo(DRC), has been a very different kind of outbreak than the massive West African outbreak that occurred in 2014 and 2015. For starters, it is much smaller, with just over 2,000 cases compared to the more than 28,000 cases of the West African outbreak. Because of […]
Study of tick-borne disease dynamics could thwart future outbreaks
The Centers for Disease Control and Prevention (CDC) released a report earlier this year on the increase of tick-, flea- and mosquito-borne illnesses in the United States, but don’t panic. Kurt Vandegrift, assistant research professor of biology at Penn State, works on emerging infectious diseases, and his lab studies ticks. Vandegrift’s lab is part of a National […]