Despite the widespread use of medical-grade computed tomography (CT) in death investigations around the world, this imaging technique is often limited in its ability to accurately depict smaller anatomical structures or trauma at the microscopic level. Recent investigations into the use of micro-CT (an imaging modality that is commonly used for industrial purposes) as a […]
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Tiny DNA reader to advance development of anticancer drugs: Researchers use tiny probes and an electrical current to locate anticancer drug molecules incorporated into single strands of DNA
DNA is small. Really, really, small. So, when researchers want to study the structure of a single-stranded DNA, they can’t just pull out their microscopes: they have to get creative. In a study published this week in Scientific Reports, researchers from Japan’s Osaka University explain how they came up with a really small solution to […]
A novel biosensor to advance diverse high-level production of microbial cell factories
A research group at KAIST presented a novel biosensor which can produce diverse, high-level microbial cell factories. The biosensor monitors the concentration of products and even intermediates when new strains are being developed. This strategy provides a new platform for manufacturing diverse natural products from renewable resources. The team succeeded in creating four natural products […]
New insights into DNA phase separation
“Each human cell contains approximately 2 meters of DNA, yet that are too small to be visible to the unaided eye. Amazingly, all of that DNA is tightly packaged into a teeny little nucleus. There, we were able to observe the most basic separation principle of oil and water phases.” A new study by Professor […]
Ancient DNA testing solves 100-year-old controversy in Southeast Asian prehistory
Two competing theories about the human occupation of Southeast Asia have been debunked by ground-breaking analysis of ancient DNA extracted from 8,000 year-old skeletons. Southeast Asia is one of the most genetically diverse regions in the world, but for more than 100 years scientists have disagreed about which theory of the origins of the population […]