The natural world often provides the answer to unsolved medical problems. On this occasion, the solution to a challenge posed by cancer has come about from the immune system of camelids. A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and the Vrije Universiteit Brussel (VUB), in Belgium, describes a number of […]
Genetics of cholesterol point to possible drug targets for heart disease, diabetes
From the DNA of nearly 300,000 veterans, scientists have singled out a handful of genetic mutations that not only govern levels of cholesterol, but may also inform the development and use of drugs for cardiovascular disease and diabetes, according to researchers at the Stanford University School of Medicine and the Palo Alto Veteran Affairs Health […]
Father Transmits HIV to Newborn Son in Rare Case: How Did It Happen?
After a 4-year-old boy in Portugal was diagnosed with HIV, the biggest question was how he got the infection. His mother, for example, didn't have it (women with HIV can pass the virus to babies). An investigation revealed a surprising source: leaky blisters on the boy's father's skin. While it's well-known that a mother can […]
New insights into DNA phase separation
“Each human cell contains approximately 2 meters of DNA, yet that are too small to be visible to the unaided eye. Amazingly, all of that DNA is tightly packaged into a teeny little nucleus. There, we were able to observe the most basic separation principle of oil and water phases.” A new study by Professor […]
Study seeks former opioid users who avoided addiction
Individuals with a history of opioid misuse — but no history of opioid addiction — may help scientists identify genes that protect against opioid-use disorders. To that end, researchers at Washington University School of Medicine in St. Louis are launching a large-scale study for which they plan to recruit 2,000 people who have used opioids […]
Cannabis link to relieving intestinal inflammation explained
Reports from cannabis users that the drug reduces the symptoms of inflammatory bowel disease (IBD) may finally be explained by new research from the University of Massachusetts Medical School and the University of Bath showing that endocannabinoids help control and prevent intestinal inflammation in mice. This is the first-time scientists have reported a biological mechanism […]
Twin study highlights importance of both genetics and environment on gene activity
New research highlights the extent to which epigenetic variation is influenced by both inherited and environmental factors. Epigenetic processes affect the expression or activity of genes without changing the underlying DNA sequence and are believed to be one mechanism by which the environment can interact with the genome. Now, an international group of researchers including […]
23andMe Is Sharing Its 5 Million Clients' Genetic Data with Drug Giant GlaxoSmithKline
Popular genetics-testing company 23andMe is partnering with drug giant GlaxoSmithKline to use people's DNA to develop medical treatments, the company announced in a blog post yesterday (July 25). During the four-year collaboration, the London-based GlaxoSmithKline will use 23andMe's genetic database to zero in on possible targets and treatments for human disease. "The goal of the […]