For children with spinal muscular atrophy (SMA), gene therapy with onasemnogene abeparvovec (Zolgensma, Novartis) provides long-lasting benefits with a favorable safety profile, new long-term follow-up data show. At a median of 5.2 years since receiving the approved therapeutic dose, onasemnogene abeparvovec provided “sustained, durable efficacy, with all patients alive and without the need for permanent […]
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Type 2 Diabetes Linked to Increased Risk for Parkinson’s
New analyses of both observational and genetic data have provided “convincing evidence” that type 2 diabetes is associated with an increased risk for Parkinson’s disease. Dr Alastair Noyce “The fact that we see the same effects in both types of analysis separately makes it more likely that these results are real — that type 2 […]
AstraZeneca, Sputnik Vaccines Face Hurdles With Annual COVID Shots
ZURICH (Reuters) – Vaccines from AstraZeneca, Russia’s Gamaleya Institute and Johnson & Johnson fight the coronavirus with another virus, leaving scientists concerned the shots may lose potency if annual inoculations become necessary to fight new variants. So-called viral vector shots – also used by several Chinese COVID-19 vaccine developers – use harmless modified viruses as […]
New, more reliable testing program rolled-out to hospital staff to curb Covid transmission rates
Frontline staff at Norfolk and Norwich University Hospitals (NNUH) are among the first in the country to benefit from the rollout of more accurate saliva tests in a bid to curb Covid transmission rates. Combined with the vaccination programme, these rapid tests should help to significantly reduce the ability of the virus to spread in […]
Study tracks genomics of lung tumor behavior
A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors. The study published in the American Journal of Respiratory and Critical Care Medicine is the largest analysis of in situ and early adenocarcinomas lesions using targeted sequencing. Pierre Massion, […]