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There are many factors influencing fetal growth—genetic, nutritional, environmental, uteroplacental, and fetal factors. In a new doctoral thesis from Karolinska Institutet, the aim was to further the understanding of the consequences of stress and smoking during pregnancy, the causes of intrauterine growth and asthma as well as the consequences of asthma on school performance and […]
Children born as a result of fertility treatment have different growth patterns to naturally-conceived children but, by the time they reach the age of 17, they are of similar height, weight and body mass index (BMI), according to research published today (Wednesday) in Human Reproduction. The study of 81,461 children from the Norwegian Mother, Father […]
A team of UT Southwestern researchers has identified a gene involved in the growth of breast cancer, a finding that could lead to potential new targets for treatment. “The gene ZMYND8 is increased in breast cancer conditions, and higher levels of the gene correlate with poor survival of breast cancer patients,” says Yingfei Wang, Ph.D., […]
Results were released today from a first-of-its-kind study examining how broiler (meat) chickens’ breeds and growth rates influence their welfare. The study eliminates any doubt that the root of chickens’ suffering is their breeding and has the potential to improve the lives of billions of chickens who currently suffer in high numbers from injuries and […]
Specialized cells at the leading edge of growing skin cancers dampen immune response and promote cancer invasion, Stanford researchers find. Targeting these cells could lead to effective therapies. An elite population of cancer cells marshal at the leading edges of a growing skin tumor to guide its metastasis and help it evade the body’s immune […]
Scientists report promising activity of a novel drug that targets a key molecular driver of clear cell renal cell carcinoma in patients with metastatic disease. Researchers from Dana-Farber Cancer Institute report a response rate of 24 percent across all risk categories of patients given an oral first-in-class agent that targets hypoxia inducible factor (HIF) 2-a, […]
The presence of a blood clot on the wall of the aorta in people with abdominal aortic aneurysms is associated with more rapid, potentially dangerous growth in the aneurysm, according to a major study published in the journal Radiology. Researchers said the findings could help identify which patients need more aggressive treatment and more frequent […]
The benefits of a daily aspirin may extend beyond heart health to colorectal cancer treatment, say City of Hope researchers who have found aspirin appears to reduce tumor growth and inhibit recurrence of the disease. The trick now, researchers say, is to determine the right dosage of aspirin that can be used as a daily […]
The cover for issue 55 of Oncotarget features Figure 3, “Romidepsin exhibits anti-tumor effect in xenograft model of DDLPS,” by Seligson, et al. Here the researchers present in silico, in vitro, and mouse xenograft studies that suggest that specifically targeting HDAC2 reduces MDM2 expression and has anti-tumor affects in DDLPS. In a murine DDLPS xenograft […]
Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that they could reengineer adipocytes—fat cells that feed fatty acids energy needed to promote tumor growth and metastasis—to reverse […]