People living with the often-debilitating effects of Crohn’s disease may finally gain some relief, thanks to ground-breaking research led by McMaster University. McMaster investigator Brian Coombes said his team identified a strain of adherent-invasive E-coli (AIEC) that is strongly implicated in the condition and is often found in the intestines of people with Crohn’s disease. […]
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Factors Associated With Suicide in Leukemia Identified
FRIDAY, Oct. 9, 2020 — Male sex, older age at diagnosis, White race, and having acute myeloid leukemia are risk factors associated with suicide among patients with leukemia, according to a study published online Oct. 6 in Cancer Medicine. Haohui Yu, from the First Affiliated Hospital of Jinan University in China, and colleagues analyzed data […]
New therapeutic target for acute kidney injury identified
Acute kidney injury (AKI) is common and it happens fast. Unlike chronic kidney disease, which often takes years to manifest, patients with AKI experience a rapid deterioration of kidney function over hours or days. Critically ill patients and those undergoing procedures that may affect the kidneys, such as coronary angiography or cardiac surgery, are at […]
Cellular origins of pediatric brain tumors identified
A research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado, of the Research Institute of the McGill University Health Centre (RI-MUHC), and Dr. Michael Taylor, of The Hospital for Sick Children (SickKids), discovered that several types of highly aggressive and, […]
Critical protein that could unlock West Nile/Zika virus treatments identified
A protein that is critical in controlling replication of West Nile and Zika viruses—and could be important for developing therapies to prevent and treat those viruses—has been identified by a Georgia State University biologist and his research group. The researchers found Z-DNA binding protein 1 (ZBP1) is a sensor that plays a significant role in […]
Close to 1,300 cases of vaping-linked illness now identified
(HealthDay)—The number of Americans sickened with a severe lung injury tied to vaping just keeps rising, U.S. health officials said Thursday. “As of Oct. 8, 2019, 1,299 confirmed and probable lung injury cases associated with use of electronic-cigarette, or vaping, products were reported by 49 states, the District of Columbia, and the U.S. Virgin Islands,” […]
Scientists have identified the presence of cancer-suppressing cells in pancreatic cancer
A research team led by Nagoya University has revealed that cells containing a protein called Meflin have a role in restraining the progression of pancreatic cancer, a type of cancer that is hard to treat with traditional anti-cancer drugs. The team has also shown that cancer progression can be limited by artificially increasing the amount […]
First case of person without the protein needed to transport vitamin D identified
Research identifying the first case of a person living without the protein needed to bind and transport vitamin D in the bloodstream has been published in the New England Journal of Medicine. The paper, led by a University of Calgary geneticist, and co-authored by researchers at the University of Washington in Seattle, U.S., and University […]
Possible biomarker for multiple sclerosis identified
A biomarker for multiple sclerosis that could be an early warning for the disease has shown promise in both human and animal testing. Researchers at Purdue University and the Indiana University School of Medicine found that acrolein, a molecule previously suspected as a metabolic waste product that accumulates in people with certain neurological disorders such […]
Ashkenazi Jewish founder mutation identified for Leigh Syndrome
Over 30 years ago, Marsha and Allen Barnett lost their sons to a puzzling childhood disease that relentlessly attacked their nervous systems and sapped their energy. After five-year-old Chuckie died suddenly in 1981, doctors provided a name for the disease: Leigh syndrome. Leigh syndrome is a complex disorder typically caused by dysfunctional mitochondria, the tiny […]