Simple blood test could identify patients at risk of developing type 2 diabetes almost 20 YEARS before the condition strikes, study claims Blood test could spot people at-risk of developing type 2 diabetes 20 years early People who with high high follistatin levels up to twice as likely to have diabetes Experts said findings could […]
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Researchers identify cell type that regulates liver regeneration with touch
From the time of Aristotle, it has been known that the human liver has the greatest regenerative capacity of any organ in the body, being able to regrow even from a 70% amputation, which has enabled live-donor transplants. Although the liver regenerates fully upon injury, the mechanisms that regulate how to activate or stop the […]
New studies identify how tuberculosis processes destroy the lungs and how to protect them
Two new studies have cast unprecedented light on disease processes in tuberculosis, identifying key genetic changes that cause damage in the lungs and a drug treatment that could speed up recovery. Tuberculosis (TB) is a lung infection that has killed more humans than any other, and until last year was the top infectious killer around […]
Researchers identify the proteins that cause intestinal disease
Researchers from Tel Aviv University have created an artificial intelligence platform that can identify the specific proteins that allow bacteria to infect the intestines—a method that paves the way for the creation of smart drugs that will neutralize the proteins and prevent disease, without the use of antibiotics. Participating in the study, which was published […]
COVID-19: Scientists identify human genes that fight infection
Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Knowing which genes help control viral infection can greatly assist researchers’ understanding of factors that affect disease severity and also suggest possible therapeutic options. The genes in question are related to interferons, the body’s […]
Extremist minds: These psychological traits might help identify people vulnerable to becoming radicalized
The characteristics of peoples’ brains might offer clues about the political beliefs they hold dear. In a study of around 350 US citizens, we examined the relationship between individuals’ cognitive traits—the unconscious ways in which their brains learn and process information from the environment—and their ideological worldviews. We found parallels between how those with extreme […]
Researchers identify new gene involved in breast cancer growth
A team of UT Southwestern researchers has identified a gene involved in the growth of breast cancer, a finding that could lead to potential new targets for treatment. “The gene ZMYND8 is increased in breast cancer conditions, and higher levels of the gene correlate with poor survival of breast cancer patients,” says Yingfei Wang, Ph.D., […]
Researchers engineer novel disease model to identify potential targets for ulcerative colitis drugs
As reported in Nature Communications, researchers from Cleveland Clinic’s Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease. The team used the model to identify a promising target that could be inhibited to slow disease progression.Ulcerative colitis is […]
Cancer researchers identify potential new class of drugs to treat blood and bone marrow cancers
A new study by researchers in Cleveland Clinic’s Taussig Cancer Institute and Lerner Research Institute describes a novel class of targeted cancer drugs that may prove effective in treating certain common types of leukemia. The results first appeared online in Blood Cancer Discovery. Myeloid leukemias are cancers derived from stem and progenitor cells in the […]
Researchers identify microRNA that shows promise for hair regrowth
Researchers from North Carolina State University have identified a microRNA (miRNA) that could promote hair regeneration. This miRNA—miR-218-5p—plays an important role in regulating the pathway involved in follicle regeneration, and could be a candidate for future drug development. Hair growth depends on the health of dermal papillae (DP) cells, which regulate the hair follicle growth […]