Cancer is complex and unpredictable. Despite successful treatment or years of remission, there is always a chance that a patient’s cancer can return. It usually happens in the form of metastasis, which is when remaining cancer cells in the body spread to another location and grow. Moffitt Cancer Center researchers are working to better understand […]
Researchers identify a moving target in small cell lung tumors
Lung cancers account for approximately 25 percent of all cancer deaths. Even among those who do not smoke, 1 in 15 men and 1 in 17 women are expected to develop lung cancer in their lifetime, according to the American Cancer Society. Lung cancer has confounded scientists who strive to develop better therapies for this […]
Training middle-school educators to identify suicide warning signs
Aside from car crashes, suicide is now the second-leading cause of death among young people in the United States, according to the Centers for Disease Control. In Ohio alone, suicide is the leading cause of death for 10- to 14-year-olds, according to new data from the state’s health department. Experts agree that among the most […]
Geneticists identify small molecules that are potential indicators for disease
A critical question in medicine asks how individual variation in DNA can predict variation in health and disease. New research from the Clemson Center for Human Genetics identified hundreds of metabolites that might serve as intermediates to translate variation in the genome to variation in complex traits. Published recently in Genome Research, the findings could one day […]
Scientists use crabs to validate popular method to identify unknown human brain neurons
“Being crabby” might have a whole new meaning. A crab’s nervous system could help scientists learn what causes single neurons in the human brain to become “out of whack,” which can contribute to the development of neurological diseases like Alzheimer’s disease. Knowing exactly how a single neuron operates among the billions housed in the human […]
Scientists identify new puberty-promoting genes
A team of neuroscientists led by Professor Christiana Ruhrberg (UCL, UK) and Professor Anna Cariboni (University of Milan, Italy) have found two molecules that work together to help set up the sense of smell and pave the way to puberty in mice. These findings, reported in the journal Development, may help our understanding of why […]
Scientists identify hormone potentially linked to hypersexual disorder
A new study of men and women with hypersexual disorder has revealed a possible role of the hormone oxytocin, according to results published in the journal Epigenetics. The finding could potentially open the door to treating the disorder by engineering a way to suppress its activity. Hypersexual disorder, or an overactive sex drive, is recognized […]
A liquid biopsy test can identify patients who may respond to immune checkpoint blockade
A new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it could help determine which patients are likely to respond to immune checkpoint inhibitors, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research. In May 2017, the U.S. Food and […]
Researchers identify key proteins for the repair of nerve fibers
Scientists at the German Center for Neurodegenerative Diseases (DZNE) have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal Neuron. It is commonly accepted that neurons of the central nervous system shut down their ability to grow when they no longer need it; this occurs […]
Researchers identify previously unrecognised abnormalities in how MND affects brain activity
Researchers in the Academic Unit of Neurology at Trinity College Dublin have identified characteristic changes in the patterns of electrical brain wave activity in motor neurone disease (MND). This ground breaking observation will help to develop treatments for the disease that affects over 350 people in Ireland. Their findings, published in the recent issue of […]