Low oxygen levels are a well-known cause of brain injury in premature babies. But the mechanism by which low oxygen hurts the developing human brain has been unclear. Now, researchers at the Stanford University School of Medicine have identified a specific set of brain cells that are particularly susceptible to harm from low oxygen exposure […]
A new approach to peripheral nerve injury? Natural killer cells in the immune system could present a target
In animal models of a totally crushed peripheral nerve, the damaged axons are broken down, allowing healthy ones to regrow. But humans rarely suffer complete axonal damage. Instead, axons tend to be partially damaged, causing neuropathic pain—a difficult-to-treat, chronic pain associated with nerve trauma, chemotherapy and diabetes. A new study in Cell, led by Michael […]
Scientists uncover five types of problem drinkers
Do you struggle to cut back on alcohol, or does it make you take risks? Scientists uncover five types of problem drinkers Researchers defined types with a set of symptoms by looking at 5,400 drinkers What category you fall into will largely depend on your age, scientists claim Pennsylvania State University experts say it could […]
Youth TBI laws promote head injury evaluation in emergency department
Millions of children and teens are affected by sports and recreation-related traumatic brain injuries (TBI) annually. To help reduce the effects of TBIs in youth sports, all 50 states and the District of Columbia enacted state youth TBI laws between 2009 and 2014. A new study from researchers in the Center for Injury Research and […]
A role for circadian enhancers to prevent myocardial injury in the perioperative setting
Innovative cardioprotective strategies are of imminent demand. Nonfatal myocardial ischemia (MI) poses a significant risk to patients undergoing major non-cardiac surgery and these non-cardiac surgeries account for around 8 million myocardial injuries per year. Considering perioperative MI is the most common major cardiovascular complication, identifying factors that lead to cardiac disease onset and finding solutions […]
Study identifies gene that makes gentle touch feel painful after injury
Ever wonder why things that normally feel gentle, like putting on soft shirts, are painful after a sunburn? In a study of four patients with a rare genetic disorder, NIH researchers found that PIEZO2, a gene previously shown to control our sense of our bodies in space and gentle touch, may also be responsible for […]
Gene signature predicts outcome after spinal cord injury
Scientists have determined a gene signature that is linked to the severity of spinal cord injury in animals and humans, according to a study in the open-access journal eLife. The discovery of key genes that are switched on or off in response to spinal cord injury could inform the development of biomarkers that predict recovery […]
Researchers discover possible cause for Alzheimer’s and traumatic brain injury
Rutgers researchers have discovered a new mechanism that may contribute to Alzheimer’s disease and traumatic brain injury. They now hope to launch a clinical trial to test the treatment in humans. What causes Alzheimer’s is unknown, but a popular theory suggests a protein known as amyloid-beta slowly builds up a plaque in the brains of […]
YAP after acute kidney injury
Acute kidney injury (AKI)—sudden and rapid failure of the kidneys—affects up to 20 percent of hospitalized patients, and up to 70 percent of ICU patients. Studies have indicated that dedifferentiation and proliferation of surviving kidney cells contributes to kidney regeneration and recovery from AKI. EGF receptor (EGFR) and Hippo signaling pathways, which regulate cell proliferation […]
If You're Reading This On Your Phone, You Probably Have Tech Neck
If you’re reading this, congratulations: You may be well on your way to chronic neck pain in the foreseeable future. Why? You’re staring at a screen, reading this. More people than ever are suffering from “tech neck,” a term used to describe neck pain directly attributed to technology use, according to the New York Post. Left unattended, tech […]