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In children with rhabdomyosarcoma, or RMS, a rare cancer that affects the muscles and other soft tissues, the presence of mutations in several genes, including TP53, MYOD1, and CDKN2A, appear to be associated with a more aggressive form of the disease and a poorer chance of survival. This finding is from the largest-ever international study […]
In the first systematic large-scale evaluation of the UK National Early Warning Risk Score (NEWS) 2 as a scoring system for predicting severe COVID-19 outcomes in patients, researchers at King’s College London have found poor-to-moderate accuracy for identifying patients at risk of being transferred to intensive care units (ICUs) or dying after 14 days of […]
The World Health Organization said Monday it had received reassurances from Beijing that international experts would soon be able to travel to China to help investigate the animal origins of COVID-19. “We fully expect and have reassurances from our Chinese government colleagues that the trip to the field… will be facilitated, and as soon as […]
Researchers from Johns Hopkins University in collaboration with Insilico Medicine announce the publication of a new research paper titled “GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma” in Science Signaling. The KEAP1-NRF2 pathway plays a key role in cancer prevention and protective cellular responses to oxidative and electrophilic stress. In normal and premalignant tissues […]
As the novel coronavirus continues to spread across the globe, countries are continuing to implement social distancing and shelter-in-place orders to prevent the spread of the virus. But as people violate these regulations, local and national governments are having to take more creative measures to keep people indoors and away from large groups of people. […]