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Cancer of the esophagus claims more than 400,000 lives around the world each year. With no efficient, reliable method of screening for the disease, by the time symptoms become apparent, it’s often too late to save the patient. A Johns Hopkins researcher who has devoted his career to the detection and prevention of esophageal cancer […]
Researchers from Karolinska Institutet in Sweden have identified a protein that determines the identity and invasive properties of breast cancer cells. The finding could lead to the development of new therapeutic and diagnostic strategies to target breast cancer invasion and metastasis. The study is published in the scientific journal Cancer Research. Cancer cell invasion of […]
Walter and Eliza Hall Institute researchers have uncovered new insights into how the normal controls on cell growth are lost in cancer cells, leading to rapid tumour expansion. The findings could help researchers predict how cancer cells respond to chemotherapy and improve our understanding of how cancer evolves. Published in the journal Cell Cycle, the […]
Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn’t obscure possible underlying cancers. Because HLH is dangerously aggressive in its progression and attack on vital organs — often causing death — doctors frequently […]
Adolescent and young adult (AYA) patients with acute lymphoblastic leukemia (ALL) were significantly more likely to relapse than pediatric ALL patients, and factors including lower clinical trial enrollment and shorter duration of therapy were associated with relapse. The study is published in the Cancer Epidemiology, Biomarkers & Prevention, by Julie A. Wolfson, MD, MSHS, assistant […]
A new study by scientists at the University of Liverpool highlights how a clinically-approved lung cancer drug could potentially be ‘repurposed’ to design new treatments for future cancer therapies. The research, published in Science Signaling, focuses on a protein called TRIB2, which is linked to promoting survival and drug resistance in solid tumours and blood […]
Hematopoietic stem cell transplantation (HSCT) is the treatment of choice for many patients with malignant and non-malignant hematological diseases, such as leukemia and multiple myeloma. The success of recent advances in such transplantation techniques and supportive care measures, has led to greater numbers of long-term HSCT survivors. Consequently, an increasing patient population is impacted by […]
THURSDAY, Sept. 13, 2018 — Lumoxiti injection has been approved to treat certain instances of relapsed or refractory “hairy cell” leukemia (HCL), the U.S. Food and Drug Administration said Thursday. Lumoxiti (moxetumomab pasudotox-tdfk) is among a novel class of drugs called CD22-directed cytotoxins to treat HCL, the agency said. It was approved for adults who […]
Certain brain cancers are associated with low numbers of immune system T-cells circulating in the peripheral blood. Low T-cell numbers can be a side-effect of cancer treatment. But it now appears that there is more to the story of these missing T-cells. Researchers from multiple institutions, including Osaka University, have now revealed how brain cancers […]
Fragility fractures are a serious yet neglected complication of both type 1 and type 2 diabetes, with increased risk of fragility fractures in people with diabetes extending across the life span. This is a concern as, globally, the prevalence of diabetes in adults is expected to increase from almost 425 million today, to approximately 629 […]