Our livers work hard to perform an entire range of activities: helping us digest food, maintaining body temperature and serving as an important checkpoint of the immune system for everything that we eat. It is inside the liver that the unique, rich and complex network of immune cells and pathways is set up to decide […]
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Exercise could be used to improve the oral environment in people with NAFLD
Liver disease, from metabolic and bacterial causes, is a growing concern. What connects these dots? The gut, or more specifically, bacteria in the gut. Bacteria that cause inflammation in the mouth are transported through the digestive tract to the gut and liver, where they can cause liver inflammation. Lipopolysaccharides, important structural molecules in some bacteria, […]
Algorithm Uses Routine Blood Tests to Detect Advanced Liver Disease
NEW YORK (Reuters Health) – It may be possible to pick up occult liver cirrhosis with an algorithm that uses data from routine blood tests, according to new research. The CIRRUS algorithm can find “a fingerprint for cirrhosis in the common blood tests done routinely by GPs,” Dr. Nick Sheron of the Foundation for Liver […]
‘Organs in a dish’ pave the way for personalized medicine in gut and liver disease
One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo. In this important review in Digestive and Liver Disease, published by Elsevier, scientists highlight some of the established and exciting novel uses for organoids or “organs […]
Movement toward a stool test for liver cirrhosis
For the estimated 100 million U.S. adults and children living with nonalcoholic fatty liver disease (NAFLD), whether or not they have liver cirrhosis, or scarring, is an important predictor for survival. Yet it’s difficult and invasive to detect liver cirrhosis before it is well advanced. In an effort to quickly and easily identify people at […]
First genetic clue for elusive pediatric liver disease: Biliary atresia with splenic malformation — connection to ciliopathy gene
A nationwide consortium of researchers has identified the first genetic defect linked to biliary atresia, a mysterious liver disease that is the leading cause for liver transplantation in children. The results were published in the journal Hepatology. The causes of biliary atresia were unknown, so this is a major advance that will move the field […]
Liver protection: Green leafy vegetables such as spinach or arugula protect us from fatty liver
Salad can prevent a fatty liver Obesity, alcohol, medications, and Diabetes can lead to fatty degeneration of the liver. Almost every third adult in Germany, the liver has a so-called fat. This is the main risk factor for the development of a dangerous cirrhosis of the liver or liver cancer. A recognized treatment, there is […]
No sweat required: Hypertension treatment mimics effect of exercise: By targeting the liver, scientists open door to new way of treating high blood pressure
Couch potatoes rejoice — there might be a way to get the blood pressure lowering benefits of exercise in pill form. Hypertension researchers at The University of Toledo have shown that by increasing the body’s supply of beta hydroxybutyrate, a chemical produced predominantly by the liver, it is possible to regulate high blood pressure without […]
Mongrel Mob gang opens up to New Zealand researchers for the good of their health
Studying the liver health of a high-risk, hard-to-reach gang population certainly came with challenges and a few surprises, a University of Otago academic says. The research, published today in Royal Society Open Science, assessed the hepatitis prevalence, knowledge, and liver health risk factors of 52 Mongrel Mob members, affiliates and extended family. Associate Professor Michael […]