We are currently witnessing the ability of vaccination programs to limit the burden of infectious disease on both individuals and society. Despite their success, most vaccines are not completely effective, and efficacy varies significantly due to individual immune response but also age and other factors. Understanding the cellular and molecular interactions that lead to a […]
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Short on sleep? Your heart may have a harder time adjusting to disruptions during sleep
Otherwise healthy adults with chronically limited sleep showed abnormal heart rate patterns in a new study published in the American Journal of Physiology-Heart and Circulatory Physiology. The study was chosen as an APS select article for October. “We really have to look at sleep as a major pillar of our overall health just like we […]
Patient-specific plates may help heal collarbone fractures
Fractures of the clavicle, or collarbone, are common. Unfortunately, current fixation plates that are used to surgically stabilize these fractures are suboptimal, leading to reoperation rates of up to 53%. A new study published in the Journal of Orthopaedic Research indicates that custom plates developed through computer modeling may be a better option. In the study, the […]
Clot-busting drug may be safe for people with stroke and unruptured aneurysms
Clot-busting drugs are the main treatment for stroke, but they have often not been recommended for people who have an aneurysm in their brains that has not ruptured. An aneurysm is a bulge in the wall of a blood vessel in the brain. A new study finds that these aneurysms rarely burst after treatment with […]
Saliva testing may allow early detection of human papillomavirus–driven head and neck cancers
Cancer causing high-risk human papillomaviruses (HR-HPV) are responsible for the rising incidence of HR-HPV–driven head and neck cancers (HNC), particularly oropharyngeal cancers (OPC, or throat cancers). Investigators have determined that HR-HPV DNA can be detected in saliva in most patients with HPV-driven OPC at the time of diagnosis. This work highlights a potentially life-saving screening […]
MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases
The mortality rate of COVID-19 patients requiring mechanical ventilation is 30-40%, however, the immunological factors associated with death in critically ill COVID-19 patients are poorly understood. A study published in PLOS Pathogens by Jonathan Youngs at St. George’s University of London, United Kingdom and colleagues suggests an association between systemic inflammation responses and increased mortality […]
Having MS plus depression may be tied to increased risk of death
Depression is common in people with multiple sclerosis (MS), and a new study shows that people with both conditions may be more likely to die over the next decade than people with just one or neither condition. The study is published in the September 1, 2021, online issue of Neurology, the medical journal of the […]
Your ZIP code may be a factor in how long you’ll stay active
Older people living in less advantaged neighborhoods become disabled roughly two years earlier than their counterparts in more affluent neighborhoods, according to a new Yale study. The findings, published Aug. 23 in the journal JAMA Internal Medicine, shed new light on the role environment plays in the disabling process. The data also point to a […]
This Much Coffee May Be Detrimental To Your Health
Coffee culture promotes endless caffeine consumption as a necessity for daily life. Between posters and Instagram accounts dedicated solely to touting the benefits of drinking coffee, it’s easy to overdo it on this seemingly harmless drink. But, coffee is loaded with caffeine which is a stimulant; over time, this can impact your brain and body […]
Cardiac atrophy findings may set course for preventing harm from long space flights
In many situations, heart muscle cells do not respond to external stresses in the same ways that skeletal muscle cells do. But under some conditions, heart and skeletal muscles can both waste away at fatally rapid rates, according to a new study led by experts at Cincinnati Children’s. The new findings, based on studies of […]