Molecules that are important for a developing fetus have also been shown to drive the spread of ovarian cancer in adult women, according to Sydney researchers. In Australia, one woman will die from ovarian cancer every 10 hours. The survival rate for women with the disease has remained at 30 per cent for years, as […]
Study shows link between teens’ copious amounts of screen time and ADHD
What with all the swiping, scrolling, snap-chatting, surfing and streaming that consume the adolescent mind, an American parent might well watch his or her teen and wonder whether any sustained thought is even possible. New research supports that worry, suggesting that teens who spend more time toggling among a growing number of digital media platforms […]
Analysis of prostate tumors reveals clues to cancer’s aggressiveness
Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common. The study lays the foundation for finding new ways to treat prostate cancer, particularly for the most aggressive forms of the disease. The multicenter study, which examined the […]
Scientists discover a mechanism of drug resistance in breast and ovarian cancer
There is a highly sophisticated way to treat some breast and ovarian cancers—a class of drugs called PARP inhibitors, designed to exploit the very defects that make tumors with certain mutations especially deadly. Yet this targeted approach to cancer therapy sometimes fails, and scientists have anxiously sought to understand why. Now, research at The Rockefeller […]
Evidence of clinical inertia in management of T2DM
(HealthDay)—Many patients with type 2 diabetes (T2D) who have a hemoglobin A1c (HbA1c) level expected to trigger treatment intensification often have treatment inappropriately delayed, according to a research letter published in the July issue of Diabetes Care. Kevin M. Pantalone, D.O., from the Cleveland Clinic, and colleagues identified a cohort of 7,389 patients with T2D […]
New platform poised to be next generation of genetic medicines
A City of Hope scientist has discovered a gene-editing technology that could efficiently and accurately correct the genetic defects that underlie certain diseases, positioning the new tool as the basis for the next generation of genetic therapies. This editing platform, discovered by City of Hope’s Saswati Chatterjee, Ph.D., eventually may be used to cure inherited […]
VA creates new Office of Electronic Health Record Modernization
The U.S. Department of Veterans Affairs established a new Office of Electronic Health Record Modernization, which will be led by Genevieve Morris, Department of Health and Human Services principal deputy national coordinator. Morris and the OEHRM will work closely with the agency’s Under Secretary of Health and CIO to manage the massive transition from the […]
About half of parents use cell phones while driving with young children in the car
A new study from a team of researchers at Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania School of Nursing (Penn Nursing) found that in the previous three months, about half of parents talked on a cell phone while driving when their children between the ages of 4 and 10 were in the […]
New protocol produces large numbers of mature human podocytes, enabling kidney disease modeling, drug discovery
Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the body. While stem cells naturally occur in very few places in the adult body, induced pluripotent stem cells (iPS cells) can be produced directly […]
The ‘Big Bang’ of Alzheimer’s: Scientists ID genesis of disease, focus efforts on shape-shifting tau
Scientists have discovered a “Big Bang” of Alzheimer’s disease – the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain. A study from UT Southwestern’s O’Donnell Brain Institute provides novel insight into the shape-shifting nature of a tau molecule just before it begins sticking to […]