Researchers at the University of Bristol and Imperial College London have established a new model system that uses red blood cells grown in the laboratory to study how malaria parasites invade red blood cells. The work, which was funded by the National Institute for Health Research and NHS Blood and Transplant and is published in […]
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Monkey malaria breakthrough offers possible cure for relapsing malaria
A breakthrough in monkey malaria research by two University of Otago scientists could help scientists diagnose and treat a relapsing form of human malaria. Malaria is a mosquito-borne infectious disease that affects humans and other animals with more than 200 million cases annually, particularly in Asia, the Pacific and South America. Symptoms include fever, tiredness, […]
Half a million tests and many mosquitoes later, new buzz about a malaria prevention drug
Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in human blood, but they don’t prevent infection or transmission via mosquitoes. What’s worse, the malaria parasite is developing resistance to existing drugs. “In many ways, the search for new malaria drugs has been a search […]
A new aspect in Plasmodium falciparum life cycle revealed: ‘Express’ sexual conversion: Conversion from the asexual to the sexual phase of the malaria parasite is necessary for its transmission to the mosquito
A study led by the Barcelona Institute for Global Health (ISGlobal) — an institution supported by “la Caixa” Foundation- reveals a new mechanism by which the malaria parasite Plasmodium falciparum converts from its asexual to its sexual form, which can be transmitted to the mosquito. The results, published in Nature Microbiology, provide important information on […]
Whole blood test for toxoplasmosis is sensitive, specific
Transmission of toxoplasmosis from mother to fetus can lead to severe congenital problems and fetal death, and tests for the parasitic infection during pregnancy are critical. Now, researchers reporting in PLOS Neglected Tropical Diseases have showed the efficacy of a low-cost whole blood test for toxoplasmosis. Toxoplasmosis results from infection with the Toxoplasma gondii parasite, […]