An international research team has developed a new method for determining cell types in a tissue sample. The scientists determined the link between the activity of genes in the same cell type and made a model capable of “recognizing” different cell types in mixed samples based on this relation. This approach works for all tissues, […]
Test can predict how people with leukaemia will respond to chemotherapy
The first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukaemia has been developed at Cardiff University. The technology could guide doctors’ decisions on which drugs to give to patients. The Cardiff researchers say that the test could now be a ‘game changer’ in […]
EEG helps scientists predict epileptic seizures minutes in advance
Elizabeth Delacruz can’t crawl or toddle around like most youngsters nearing their second birthday. A rare metabolic disorder that decimated her mobility has also led to cortical blindness—her brain is unable to process images received from an otherwise healthy set of brown eyes. And multiple times a day Elizabeth suffers seizures that continually reduce her […]
New method may better predict the best treatment for burn wounds
According to the World Health Organization, approximately 180,000 deaths every year are caused by burns, with the majority occurring in low- and middle-income countries. Upon arriving at the emergency room with a burn, the patient undergoes a clinical inspection to assess both the severity of the lesion in relation to the affected area of the […]
Simple test may help predict long-term outcome after stroke
A simple test taken within a week of a stroke may help predict how well people will have recovered up to three years later, according to a study published in the October 17, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology. “We found that this test, which takes less […]
Inflammation biomarker in blood may help predict effectiveness of depression drugs
People living with mental health disorders who benefit from medication may try several types before finding a solution that helps manage their symptoms. But what if a simple blood test could help doctors understand what medication might work best for patients at the start of their treatment? That’s an idea gaining traction and the focus […]
New genetic variants predict outcome in dilated cardiomyopathy patients of African descent
Genetic testing is a powerful diagnostic tool that is increasingly being used for the diagnosis of dilated cardiomyopathy, a disease in which the heart becomes enlarged, making it difficult to pump blood. Cardiomyopathy affects more than 3.5 million people in the United States. African Americans are at especially high risk but have been underrepresented in […]
Together, big data, bench science and genome-wide diagnostics predict genomic instability that can lead to disease
They are the most common repeated elements in the human genome; more than a million copies are scattered among and between our genes. Called Alu elements, these relatively short (approximately 300 Watson-Crick base pairs), repetitive non-coding sequences of DNA have been implicated in the rapid evolution of humans and non-human primate species. Unfortunately, these repeats […]
A new climate model can predict dengue outbreaks in the Caribbean region
Changes in climate, such as rain and drought, can affect the risk of mosquito-borne diseases including dengue, chikungunya and Zika. An international team comprising the Barcelona Institute for Global Health (ISGlobal) has developed a new tool to predict the impact of droughts and extreme rainfall on the risk of dengue outbreaks. In recent years, the […]
A better way to predict heart attacks and strokes in space
Researchers may have developed a more reliable way to predict the risk of heart attack and stroke in astronauts – and the technique may eventually help gauge the same danger for regular folks on Earth, too. NASA astronauts currently undergo a special screening method that scans coronary arteries for a buildup of calcified plaque. This […]