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A major international study has shown that opening all clogged arteries with stents after a serious heart attack is much better than opening only the single clogged artery that caused the heart attack. About half of all heart attack victims are found to have additional clogged arteries in addition to the one that caused their […]
For decades, biomedical researchers have used mouse behavior to study pain, but some researchers have questioned the accuracy of the interpretations of how mice experience pain. Now, Rutgers University-Camden neuroscientist Nathan Fried and colleagues from the University of Pennsylvania have developed a method that can more accurately gauge pain in mice, which could lead researchers […]
Researchers have discovered a key clue into the development of the pancreas and brain by studying rare patients born without a pancreas. The study from the Wellcome Sanger Institute, the University of Exeter and collaborators also identified a previously unexpected pathway involved in the development of the human pancreas, and confirmed this in mice. Understanding […]
Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease—Duchenne muscular dystrophy (DMD)—for more than a year in mice, despite observed immune responses and alternative gene editing outcomes. The study appears online on February 18 in the journal Nature Medicine. In […]
Fear. Anxiety. Hope. Desire. Love. Anger. Guilt. Grief. These are the gamut of human emotions universal to our experiences. But why some people can become vulnerable to extreme bad feelings and other mental disorders remains a mystery that has affected and divided families, and cost lost years, or worse, lives, for millions of sufferers of […]
Group A Streptococcus (GAS), sometimes known as “flesh-eating bacteria,” causes invasive infections that result in high mortality. GAS is susceptible to many antibiotics, but continues to cause devastating infections. Many studies have attempted to understand the mechanism for immune recognition of GAS, but none has provided a clear explanation, until now. In a new study […]
A new British Journal of Psychology study has looked at the details behind how cognitive performance may improve during aerobic exercise. Electroencephalography readings were taken as 24 participants performed a visual working memory task while at rest and during exercise involving different postures: seated on or pedalling a stationary bicycle, as well as standing or […]
In the brain, as in business, connections are everything. To maintain cellular associates, the outer surface of a neuron, its membrane, must express particular proteins—proverbial hands that reach out and greet nearby cells. And, like a creepily long handshake, surface molecules can overstay their welcome: A protein that lingers too long on the membrane may […]
Scientists at The Wistar Institute have applied their synthetic DNA technology to engineer a novel eCD4-Ig anti-HIV agent and to enhance its potency in vivo, providing a new simple strategy for constructing complex therapeutics for infectious agents as well as for diverse implications in therapeutic delivery. This critical development was published online in the journal […]
Researchers at Indiana University have found early evidence that tiny snippets of genetic material called microRNA may help with early detection of conditions such as Alzheimer’s disease. The study, published June 18 in Scientific Reports, found that changes in microRNA are detectable in mice long before they start to show symptoms from neurodegeneration. These microRNA […]