In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs. While studying a mouse model that replicates key features of early-stage human breast cancer, […]
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Researchers discover coffee drinkers could halve their risk of liver cancer
A research team from Queen’s University has found that coffee drinkers have a lower risk of the most common type of liver cancer, hepatocellular carcinoma (HCC). The results have been presented at the National Cancer Research Institute (NCRI) conference in Glasgow this week and was published in British Journal of Cancer earlier this year. Coffee […]
Researchers find molecular mechanisms behind women’s biological clock
Researchers have mapped out some of the mechanisms that may affect women’s fertility from the teenage years to menopause. These mechanisms largely depend on naturally occurring chromosome errors—errors that vary depending on age group. This is the conclusion by an international research group in a new study, led by researchers from the University of Copenhagen. […]
Researchers discover a new defensive mechanism against bacterial wound infections
Wound inflammation that results in impaired wound healing can have serious consequences for patients. Researchers from Charité – Universitätsmedizin Berlin have discovered a new defensive mechanism that enables skin to actively kill bacteria. Central to this mechanism is a cellular messenger molecule known as interleukin 6, whose mode of action may be used in the […]
Researchers show 20 mph zones effective in reducing road casualties
A review of published evidence by Queen’s University Belfast has found 20mph zones to be effective in reducing the number and severity of traffic collisions and casualties. The research, published in the Journal of Transport and Health provides important evidence to support the implementation of 20mph speed zones across the UK and Europe. The research, […]
Researchers apply fat cells to deliver drug to suppress tumor growth
Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that they could reengineer adipocytes—fat cells that feed fatty acids energy needed to promote tumor growth and metastasis—to reverse […]
Researchers isolate switch that kills inactive HIV
Using genetic sequencing, University of California San Diego School of Medicine researchers have identified a principal cellular player controlling HIV reproduction in immune cells which, when turned off or deleted, eliminates dormant HIV reservoirs. “This is one of the key switches that the HIV field has been searching for three decades to find,” said Tariq […]
Researchers describe a key protein for Epstein-Barr virus infection
Scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the Molecular Biology Institute of Barcelona (IBMB-CSIC) have published a study in the journal Nature Communications revealing the structure of a key protein, known as a portal, in Epstein-Barr virus infection. The Epstein-Barr virus, which belongs to the herpesvirus family, is one of the […]
Researchers discover previously unidentified mechanisms of obesity-induced insulin resistance
A research team at the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), has discovered the potentials of a SECISBP2 protein in adipose tissue macrophages (ATMs) as a therapeutic biomarker in the treatment of chronic diseases such as type 2 diabetes, hyperlipidemia, cardiovascular diseases and cancers caused by obesity-induced insulin resistance. The findings, […]
Researchers identify key proteins for the repair of nerve fibers
Scientists at the German Center for Neurodegenerative Diseases (DZNE) have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal Neuron. It is commonly accepted that neurons of the central nervous system shut down their ability to grow when they no longer need it; this occurs […]