An international team of researchers from the Institute for Research in Biomedicine, affiliated to the Università della Svizzera italiana, has deciphered the T cell responses occurring during COVID-19 infection at single-cell resolution. This study, which was performed at the Center of Medical Immunology under the leadership of Prof. Federica Sallusto, included collaborations with clinical institutions […]
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Gut microbiome may influence how cancer patients respond to oral therapies, study suggests
A new study from Lawson Health Research Institute and Western University illustrates how the gut microbiome interacts with an oral medication in prostate cancer patients, suggesting bacteria in the gut play a role in treatment outcomes. The findings, published in Nature Communications, highlight how the drug abiraterone acetate is metabolized by bacteria in the gut […]
A liquid biopsy test can identify patients who may respond to immune checkpoint blockade
A new liquid biopsy test could detect microsatellite instability (MSI) and tumor mutational burden (TMB), indicating that it could help determine which patients are likely to respond to immune checkpoint inhibitors, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research. In May 2017, the U.S. Food and […]
Test can predict how people with leukaemia will respond to chemotherapy
The first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukaemia has been developed at Cardiff University. The technology could guide doctors’ decisions on which drugs to give to patients. The Cardiff researchers say that the test could now be a ‘game changer’ in […]