University of Colorado Cancer Center led clinical trial data show that a predictive tool called COXEN may show which bladder cancer patients will respond to pre-surgical chemotherapy, a step towards allowing doctors to offer such chemotherapy to patients likely to respond, while moving more efficiently to other treatment options with patients unlikely to benefit. Results […]
Inside the ASPCA's Response to Hurricane Florence
In the wake of Hurricane Florence, ASPCA responders remain on the ground in North Carolina to continue to assist animals displaced by the storm and the communities impacted. In the past week, we’ve conducted animal search-and-rescue, brought food and supplies to pets in need, and worked tirelessly alongside local agencies to provide emergency sheltering for […]
Pain response in babies’ brains controlled in ‘similar way to adults’
Researchers from the Department of Paediatrics and Wellcome Centre for Integrative Neuroimaging at the University of Oxford, UK, have identified the neural network that helps control babies’ brain activity in response to pain in a similar way to adults. Their findings build on their previous study from 2015, which revealed that newborns experience pain like […]
Research team develops predictor for immunotherapy response in melanoma
In a new study, researchers developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors, a novel type of immunotherapy. The predictor was developed by Noam Auslander, Ph.D., with other researchers in the Center for Cancer Research (CCR) at the National […]
Serena Williams Had the Best Response to a Coach Who Said to Stop Breastfeeding
Legendary tennis player Serena Williams is a force to be reckoned with, especially as a parent. The seven-time Wimbledon winner recently sat down with Time magazine and recalled an instance when her coach, Patrick Mouratoglou, told her to stop breastfeeding her newborn daughter, Alexis Olympia — so that she could refocus her efforts on tennis. […]
‘Hijacked’ cell response to stress reveals promising drug targets for blood cancer
A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows. The discovery that the NOTCH1 pathway takes control of heat shock transcription factor 1 (HSF1) signaling in T cell acute lymphoblastic leukemia, or […]
Study describes enzyme’s key role in immune response to Chagas disease parasite
In an article published recently in the journal Nature Communications, researchers affiliated with the University of São Paulo (USP) in Brazil describe the central role played by an enzyme called phosphatidylinositol 3-kinase gamma (PI3Kγ) in regulating the immune response against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease. “Our results show that the expression […]
This Married Woman’s Incredible Response To A Cheating Husband Has Gone Viral
When a married woman was messaged by a man asking her if she would like to “go out sometime,” initially, she was flattered. She replied in a polite manner, saying that she was married, but if she wasn’t he did genuinely seem like “a catch.” However, she was seriously mistaken. After clarifying she was indeed taken, […]