A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests. The finding, published online in Cell Metabolism, could help explain the “obesity paradox,” a phenomenon in which obese individuals have better short- and medium-term cardiovascular disease prognoses compared with those who […]
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When does a bruise on an infant or young child signal abuse?
Bruising caused by physical abuse is the most common injury to be overlooked or misdiagnosed as non-abusive before an abuse-related fatality or near-fatality in a young child. A refined and validated bruising clinical decision rule (BCDR), called TEN-4-FACESp, which specifies body regions on which bruising is likely due to abuse for infants and young children, […]
“Rare” or “Exotic” Puppies Signal Red Flags
“Rare” or “exotic” puppies with unusually patterned or colored coats may seem enticing—but these striking and unusual qualities could signal a problem. Considering buying a dog who is “unusual,” “exotic” or “rare?” It’s critical that you dig deeper into where the puppy came from by researching the breeder and their breeding program. While puppies can […]
Eyes send an unexpected signal to the brain
The eyes have a surprise. For decades, biology textbooks have stated that eyes communicate with the brain exclusively through one type of signaling pathway. But a new discovery shows that some retinal neurons take a road less traveled. New research, led by Northwestern University, has found that a subset of retinal neurons sends inhibitory signals […]
Fatty food turns off a signal in the brain that says you are full
Why you crave a second helping: High-fat food turns off a signal in the brain that tells you when you are full, study in mice shows Researchers at Baylor College of Medicine uncovered a previously unknown gut-brain connection Mice consuming a high-fat diet had higher levels of a hormone (called GIP) that manages energy balance […]
Bacteria in fermented food signal the human immune system, explaining health benefits
Researchers have discovered that humans and great apes possess a receptor on their cells that detects metabolites from bacteria commonly found in fermented foods and triggers movement of immune cells. Claudia Stäubert of the University of Leipzig and colleagues report these findings in a new study published 23rd May in PLOS Genetics. Consuming lactic acid […]
Astrocytes regulate signal speeds of neurons
The transmission speed of neurons fluctuates in the brain to achieve an optimal flow of information required for day-to-day activities, according to a National Institutes of Health study. The results, appearing in PNAS, suggest that brain cells called astrocytes alter the transmission speed of neurons by changing the thickness of myelin, an insulation material, and […]
Abdominal aortic calcification may signal future heart attack
Computed tomography (CT)-based measures of calcification in the abdominal aorta are strong predictors of heart attacks and other adverse cardiovascular events—stronger even than the widely used Framingham risk score, according to a new study published in the journal Radiology. Cardiovascular diseases are the leading cause of death worldwide. Of these deaths, heart disease and stroke […]