Walter and Eliza Hall Institute researchers have uncovered new insights into how the normal controls on cell growth are lost in cancer cells, leading to rapid tumour expansion. The findings could help researchers predict how cancer cells respond to chemotherapy and improve our understanding of how cancer evolves. Published in the journal Cell Cycle, the […]
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Heart attack: Substitute muscle thanks to stem cells
Myocardial infarction — commonly known as a heart attack — is still one of the main causes of death. According to the Federal Statistical Office, more than 49,00 people died of its consequences. And yet the mortality after heart attack has greatly decreased over the past decades: As compared to the early 1990s, it has […]
Canine melanoma study identifies genetic basis of disease; potential drug targets: Discoveries among dogs could someday lead to improved genome-based cancer treatments for both dogs and humans
As a veterinarian, Dr. Carolyn Duregger is familiar with the telltale signs of canine melanoma. So when she gave her own dog, Parker, a routine oral examination, the 1-centimeter-diameter discolored lump in the pup’s upper right gums took her breath away. “It’s an aggressive cancer with poor prognosis that I’ve seen many times. My stomach […]
How our immune system detects broken DNA: Skin cells alert the immune system, when their DNA is damaged in the absence of infection
Our immune system is working every day to protect us from bacteria, viruses, and parasites, but it can also detect when our own cells are damaged. Research led by Lancaster University has now discovered how skin cells alert the immune system, when their DNA is damaged in the absence of infection. This DNA damage can […]
Novel role of protein in important pathways that lead to cancer malignancy
Japanese researchers have revealed for the first time that a specific protein plays a critical role in the development and metastasis of highly aggressive prostate and breast cancer cells. The study reports that large amounts of the fatty acid-binding protein 5 (FABP5), a kind of transport protein for fatty acids, promotes processes associated with cancer […]
Common skin cancer can signal increased risk of other cancers
People who develop abnormally frequent cases of a skin cancer known as basal cell carcinoma appear to be at significantly increased risk for the development of other cancers, including blood, breast, colon and prostate cancers, according to a preliminary study by researchers at the Stanford University School of Medicine. The increased susceptibility is likely caused […]