More than three decades after they were found to have elevated blood lead levels as children, a group of middle-aged adults were found to have some small but significant changes in brain structure that corresponded to their dose of lead exposure in early life. MRI scans at age 45 revealed some small but significant changes […]
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Alterations in hippocampal structural connections differentiate responders of electroconvulsive therapy
A new study in people with major depression reports that electroconvulsive therapy (ECT) induces changes in the fibers connecting the hippocampus to brain regions involved in mood and emotion. Only patients who responded to the treatment showed these changes, and those who had the greatest changes in hippocampal pathways also showed the largest improvements in […]
Drugs that block structural changes to collagen could prevent lung fibrosis
Scientists have found that it is the structure of collagen, rather than the amount, that leads to the devastating condition of lung fibrosis, according to a report in the journal eLife. The study provides the first evidence in humans that altered collagen structure affects tissue stiffness during progression of lung fibrosis and identifies a potential […]