Treating mice that have a Parkinson’s disease-causing mutation with a small molecule compound restores the removal of damaged mitochondria from their brain cells, shows a study published today in eLife. The findings may help explain what goes wrong in dopamine-producing brain cells in people with mutations that cause Parkinson’s disease. Parkinson’s disease is caused by […]
Diabetes: Study of satiety mechanism yields new knowledge
Diabetes, a disease in which blood sugar levels remain too high for too long, can lead to health complications in the long term. Type 2 diabetes (T2D) accounts for 90% of cases. Patients are usually obese or overweight, with risk factors that include sedentary lifestyle and unbalanced diet. To increase their understanding of the disease, […]
New study reveals serious long-term complications in youth-onset type 2 diabetes
Phil Zeitler, MD, Ph.D., has been treating youth with type 2 diabetes for more than 20 years. He and a team of researchers published a paper today on the TODAY2 study in the New England Journal of Medicine on the long-term complications of type 2 diabetes. (TODAY stands for Treatment Options for type 2 Diabetes […]
Study finds lifting advice doesn’t stand up for everyone
Commonly accepted advice to keep a straight back and squat while lifting in order to avoid back pain has been challenged by new Curtin University research. The research examined people who had regularly performed manual lifting through their occupation for more than five years and found those who experienced low back pain as a result […]
Study: Long-term prognosis for some patients with severe brain injury better than expected
New research adds to a body of evidence indicating decisions about withdrawing life-sustaining treatment for patients with moderate-to-severe traumatic brain injury (TBI) should not be made in the early days following injury. In a July 6, 2021, study published in JAMA Neurology, researchers led by UC San Francisco, Medical College of Wisconsin and Spaulding Rehabilitation […]
Study shows low COVID-19 infection rate in health care workers
Antibody testing of health care workers in three rural counties in eastern South Dakota and western Minnesota showed 15% of the study participants had antibodies to the novel coronavirus. “Antibodies (to the novel coronavirus) show the true prevalence (of COVID-19) in the population,” according to South Dakota State University assistant professor Natalie Thiex, whose research […]
International study of rare childhood cancer finds genetic clues, potential for tailored therapy
In children with rhabdomyosarcoma, or RMS, a rare cancer that affects the muscles and other soft tissues, the presence of mutations in several genes, including TP53, MYOD1, and CDKN2A, appear to be associated with a more aggressive form of the disease and a poorer chance of survival. This finding is from the largest-ever international study […]
Study highlights need to address mental health of new fathers
While postpartum depression in new mothers is well recognized and known to increase if the newborn requires intensive care, depression in new fathers has not received much attention. A large study, published in the journal Pediatrics, found that both parents with a baby in the NICU are at risk, with depression symptoms identified in 33 […]
Study reveals how Y-box binding protein 1 promotes cancer metastasis
Metastasis of cancer is the main cause of cancer relevant death as well as the main challenge of cancer treatment. Recently, a group led by Prof. Piao Hailong from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS) revealed that the nucleotide binding protein Y-box binding protein 1 (YB1) can […]
Study helps explain how religious beliefs are formed
Feeling anxious can direct our attention and memory toward supernatural beings such as gods, a University of Otago study has found. Lead author Dr. Thomas Swan, of the Department of Psychology, says the research may help explain how religious beliefs are formed. For the study, published in the International Journal for the Psychology of Religion, […]