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The aggregation of alpha-synuclein proteins in Parkinson’s disease and tau proteins in Alzheimer’s disease is intimately linked to the progression of these neurodegenerative diseases. These aggregates propagate from one neuronal cell to another, attaching themselves to the cells. They multiply during this propagation. It has already been shown that the propagation and amplification of these […]
Scientists have invented a high-sensitive smart syringe, the changes in the tissue and detects it in delicate cases, it easier to hit the target better. Example, medications can be administered in the sensitive areas of the eye. In animal experiments, the device was already tested successfully. In some regions of the body, a specialist is […]
In animal models of a totally crushed peripheral nerve, the damaged axons are broken down, allowing healthy ones to regrow. But humans rarely suffer complete axonal damage. Instead, axons tend to be partially damaged, causing neuropathic pain—a difficult-to-treat, chronic pain associated with nerve trauma, chemotherapy and diabetes. A new study in Cell, led by Michael […]
A novel drug is being touted as a major step forward in the battle against Australia’s escalating rates of obesity and associated metabolic diseases. As it stands, 2 in 3 adults in Australia are classified as being overweight or obese. A long-term study between researchers at the Centenary Institute and UNSW Sydney has led to […]
Research led by Suresh Alahari, Ph.D., Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has shown for the first time that a tiny piece of RNA deregulates energy metabolism, an emerging hallmark of cancer. The finding identifies a new target for therapeutic intervention in breast cancer. The research is […]
Know your target. Especially if your target is coming into focus for treating diseases such as schizophrenia and treatment-resistant depression. NMDA receptors, critical for learning and memory, are sensors in the brain. Studying them in molecular detail is challenging, because they usually come in four parts, and the parts aren’t all the same. Researchers at […]