Scientists at the Johns Hopkins Kimmel Center say they have affirmed widespread inconsistencies in the use of a common laboratory procedure called immunohistochemical staining, and say the variations are making many laboratory experiments unreliable. Their findings were outlined in a special issue of the Asian Journal of Urology. In a review of papers published about […]
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Widely used reference for the human genome is missing 300 million bits of DNA
For the past 17 years, most scientists around the globe have been using the nucleic acid sequence, or genome, an assembly of DNA information, from primarily a single individual as a kind of “baseline” reference and human species representation for comparing genetic variety among groups of people. Known as the GRCh38 reference genome, it is […]