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Aagenaes syndrome is a rare disorder characterized by impaired bile flow from the liver resulting in cholestasis. Image Credit: Magic Mine/Shutterstock.com Blockage of bile secretion (hepatic cholestasis) results in swelling and fluid retention (lymphedema) in the lower extremities. Neonatal cholestasis in patients with Aagenaes syndrome usually diminishes during early childhood, but remains intermittent in nature. […]
Sorbitol is a naturally occurring sweetener synthetically extracted from glucose. Owing to its low calorific value, it is used in pharmaceutical products, sugar-free foods, and oral care products such as mouth fresheners and toothpastes. It is prescribed for use by diabetes patients as it has a lesser tendency to increase the sugar level in the […]
Vulvar intraepithelial neoplasia (VIN) is a pre-cancerous condition caused by a rapid increase in atypical basal cells in the vulvar epithelium. Treatment is suggested for all vulvar HSIL (VIN usual type) affected women. Credit: Pr Image Factory/ Shutterstock.com Due to possible occurrence of occult invasion and when there exists a doubt about the presence of […]
Follicular lymphoma (FL) is an indolent tumor of the lymphatic system, which may often remain inactive for years before undergoing transformation into an aggressive tumor. After treatment, a high percentage of patients fail to respond, and these tumors are categorized as refractory lymphomas. Some respond with an initial positive change, but then develop signs of […]
It is imperative to seek dental treatment following the onset of dental pain. However, some home care treatments can soothe dental pain till professional treatment is available. Damir Khabirov | Shutterstock Why am I experiencing toothache? Statistics reveal that worldwide 60-90% of school children suffer from dental caries; the most common infective human disease. Untreated […]
Coconut oil has been one of the most important fats used in the diet in Asian and African countries which have a long coastline, due to the abundance of this very useful oil palm in such regions. Fats are an essential part of the diet because of their intrinsic value as structural and functional components […]
Progressive supranuclear palsy (PSP) is a rare brain disorder that affects approximately 6 in 100,000 people worldwide. It causes muscle weakness and affects gait, balance and overall movement, as well as the patient’s mood, cognitive skills and behavior. While no treatment is available at this time, various symptoms can be managed with the use of […]
Cirrhosis is a severe form of liver disease wherein normal liver tissue is replaced by scar tissue (fibrous tissue). What changes occur in cirrhosis? Cirrhosis or fibrosis of the liver can occur due to several liver-related diseases and conditions, such as hepatitis, non-alcoholic fatty liver disease, and excessive alcohol consumption. The replacement of healthy liver […]
Pharmacoproteomics is a rapidly advancing field in which the techniques of proteomics are applied to develop pharmaceutical agents. The word itself was coined only in 1997. However, this branch of study plays a major role in personalized medicine. The word proteomics itself means the study of proteomes, a proteome being the full complement of proteins […]
Prion diseases, also known as transmissible spongiform encephalopathies (TSEs) are dreaded neurological diseases with a progressive course, and are invariably fatal. They are caused by tiny particles primarily composed of a pathogenic protein which is actually an abnormal variant of the PrP protein, a normal component of the cell membrane. Prions are unique in being […]