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Multiplex immunoassays and enzyme-linked immunosorbent assays (ELISA) are used to determine and analyze the presence of an analyte in a sample through the binding of complimentary antigen-antibody pairs. Multiplex immunoassays are useful in cases of limited sample volume or time. molekuul_be | Shutterstock Multiplex immunoassays can be differentiated by the surface to which the antigens […]
ChIP-seq, or chromatin immunoprecipitation and sequencing, is a technique that allows researchers to understand transcriptional regulation via mapping of protein-DNA interactions and epigenetic markers on a genome-wide scale. ChIP-seq has several advantages over previous methods, such as ChIP-chip, but like all techniques, ChIP-seq has its limitations. urfin | Shutterstock ChIP-seq ChIP-seq was one of the […]
(HealthDay)—Fewer than 10 percent of the U.S. adult population formed antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first wave of the pandemic, according to a study published online Sept. 25 in The Lancet. Shuchi Anand, M.D., from the Stanford University School of Medicine in Palo Alto, California, and colleagues conducted a […]
With millions of COVID-19 cases reported across the globe, people are turning to antibody tests to find out whether they have been exposed to the coronavirus that causes the disease. But what are antibodies? Why are they important? If we have them, are we immune to COVID-19? And if not, why not? Antibody tests look […]
Antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis, researchers from Karolinska Institutet in Sweden report. The researchers believe that the finding, which is published in the Journal of Experimental Medicine, can represent a general mechanism in autoimmunity and that the results can […]
Researchers from the University of Oxford, along with partners from five institutions around the world, have identified the human antibodies that prevent the malaria parasite from entering blood cells, which may be key to creating a highly effective malaria vaccination. The results of the study were published today in the journal Cell. “Following an infectious […]
Scientists at the Johns Hopkins Kimmel Center say they have affirmed widespread inconsistencies in the use of a common laboratory procedure called immunohistochemical staining, and say the variations are making many laboratory experiments unreliable. Their findings were outlined in a special issue of the Asian Journal of Urology. In a review of papers published about […]
Researchers from the National Institutes of Health have discovered that antibodies that may form the basis of a universal flu vaccine inhibit a second viral protein in addition to the one that they bind. The study, to be published January 25 in the Journal of Experimental Medicine, reveals that antibodies that recognize the viral surface […]
Researchers at Vanderbilt University Medical Center have isolated the first human monoclonal antibodies that can neutralize norovirus, the leading cause of acute gastrointestinal illness in the world. These antibodies, described this week in the journal Gastroenterology, “have high potential” for improving diagnosis and treatment of norovirus illness as well as furthering efforts to develop the […]