People who had received a first dose of the Oxford-AstraZeneca COVID-19 vaccine and received an mRNA vaccine for their second dose had a lower risk of infection compared to people who had received both doses of the Oxford-AstraZeneca vaccine. This is shown in a nationwide study performed by researchers at Umeå University, Sweden. Having received […]
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NIH awards more than $8 million to support seven high-risk, high-reward projects at Penn Medicine
The National Institutes of Health has awarded grants to researchers in the Perelman School of Medicine at the University of Pennsylvania to support "highly innovative and broadly impactful" biomedical science through the NIH Common Fund's High-Risk, High-Reward Research program. The seven awards total approximately $8.2 million over five years, The High-Risk, High-Reward Research program catalyzes […]
2 win medicine Nobel for showing how we react to heat, touch
Two scientists won the Nobel Prize in medicine on Monday for their discoveries into how the human body perceives temperature and touch, revelations that could lead to new ways of treating pain or even heart disease. Americans David Julius and Ardem Patapoutian identified receptors in the skin that respond to heat and pressure. Their work […]
Researchers develop new biomaterial that regrows blood vessels and bone
Scientists have developed a new biomaterial that regrows blood vessels and bone, potentially providing a single-stage approach when repairing large bone defects. The study, led by researchers from RCSI University of Medicine and Health Sciences and SFI AMBER Centre, is published in the Journal of Controlled Release. Previous RCSI-led research had found that activating a […]
CD40 drug before surgery can benefit patients with early-stage pancreatic cancer
Giving early-stage pancreatic cancer patients a CD40 immune-stimulating drug helped jumpstart a T cell attack to the notoriously stubborn tumor microenvironment before surgery and other treatments, according to a new study from researchers in the Abramson Cancer Center (ACC) at the University of Pennsylvania. Changing the microenvironment from so-called T cell "poor" to T cell […]
Sleep apnea treatment linked to lower risk of Alzheimer's and other dementias
A new study finds older adults who received positive airway pressure therapy prescribed for obstructive sleep apnea may be less likely to develop Alzheimer's disease and other kinds of dementia. Researchers from Michigan Medicine's Sleep Disorders Centers analyzed Medicare claims of more than 50,000 Medicare beneficiaries ages 65 and older who had been diagnosed with […]
Microrna-29 molecule controls brain maturation in mammals
A team led by scientists at the UNC School of Medicine identified a molecule called microRNA-29 as a powerful controller of brain maturation in mammals. Deleting microRNA-29 in mice caused problems very similar to those seen in autism, epilepsy, and other neurodevelopmental conditions. The results, published in Cell Reports, illuminate an important process in the […]
New study aims to develop population-based dietary assessment mobile app
Excessive intakes of saturated fat and added sugar are a leading cause of premature mortality among adults in the U.S., contributing to nearly 700,000 deaths each year, but nutritional research aimed at improving health is often challenging due to limitations in accurately tracking participants' food intake. A new University of Arizona Health Sciences-led study aims […]
New study aims to develop population-based dietary assessment mobile app
Excessive intakes of saturated fat and added sugar are a leading cause of premature mortality among adults in the U.S., contributing to nearly 700,000 deaths each year, but nutritional research aimed at improving health is often challenging due to limitations in accurately tracking participants' food intake. A new University of Arizona Health Sciences-led study aims […]
Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants
There have been concerns that several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have mutations that allow them to evade the immune system. A new study published in the Open Forum Infectious Diseases suggests otherwise. Led by Aaron AR Tobian of Johns Hopkins University School of Medicine, results showed that except for one from […]