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A simple dietary supplement reduces behavioral symptoms in mice with a genetic mutation that causes schizophrenia. After additional experiments, including visualizing the fluorescently stained dancing edge of immature brain cells, researchers concluded that the supplement likely protects proteins that build neurons’ cellular skeletons. The supplement betaine was first isolated from sugar beets and is often […]
Trillions of commensal microbes live on the mucosal and epidermal surfaces of the body and it is firmly established that this microbiome affects its host’s tolerance and sensitivity of the host to a variety of pathogens. However, host tolerance to infection with pathogens is not equally developed in all organisms. For example, it is known […]
It is necessary to develop additional COVID-19 vaccines, as different vaccine approaches have their advantages and disadvantages and may work synergistically. Researchers at Karolinska Institutet in Sweden now report that they have developed a prototype vaccine against SARS-CoV-2 using a DNA vaccine platform that is inexpensive, stable, easy to produce, and shows a good safety […]
A combination of innate differences and diet-induced changes to the reward system may predispose some mice to overeat, according to research recently published in JNeurosci. Food is fuel, but the rising levels of sugar and fat in modern diets make the brain treat it as a reward. One brain region called the ventral pallidum (VP) […]
New experimental coronavirus vaccine prevented severe disease in mice after two doses of the jab boosted their antibody levels 90-fold Researchers genetically modified vesicular stomatitis virus (VSV), which causes a mild illness in livestock, to become a vaccine The team took out a gene from VSV and inserted the spike protein from the coronavirus, which […]
When Wei Hsi (Ariel) Yeh was a young undergraduate student, one of her close friends went from normal hearing to complete deafness in the span of one month. He was 29 years old. No one knew why he lost his hearing; doctors still don’t know. Frustrated and fearful for her friend, Yeh, who graduated last […]
The older we get the more our brains will find it difficult to learn and remember new things. The research group led by Professor Federico Calegari used a method to stimulate the small pool of neural stem cells that reside in the brain in order to increase their number and the number of neurons generated […]
Increasing levels of a simplified version of “good” cholesterol reversed disease in the blood vessels of mice with diabetes, a new study finds. Published online in the journal Circulation on September 30, the study results revolve around atherosclerosis, a condition where high levels of cholesterol cause “plaques” to form in vessel walls, eventually restricting blood […]
When it comes to protecting the newborn brain, taking steps to mitigate risk before birth may be critical. Some newborns, such as those with intrauterine growth restriction (IUGR), are at heightened risk. Being able to intervene before birth to aid in protecting the newborn brain may prevent the often-devastating effects of brain injury. In ongoing […]
For decades, biomedical researchers have used mouse behavior to study pain, but some researchers have questioned the accuracy of the interpretations of how mice experience pain. Now, Rutgers University-Camden neuroscientist Nathan Fried and colleagues from the University of Pennsylvania have developed a method that can more accurately gauge pain in mice, which could lead researchers […]