A University of North Texas researcher and a 16-year old student are working together to fight cancer with mathematics. Julia Christina Ayalde Camacho, a student in the Texas Academy of Mathematics and Science and Xuexia Wang, an associate professor and researcher of statistics in UNT’s Department of Mathematics, are working together as mentor and student […]
Computer model shows how to better control MRSA outbreaks
A research team led by scientists at the Columbia University Mailman School of Public Health report on a new method to help health officials control outbreaks of methicillin-resistant Staphylococcus aureus, or MRSA, a life-threatening antibiotic-resistant infection often seen in hospitals. The researchers are the first to reveal the invisible dynamics governing the spread of these […]
Innovative model helps kids on autism spectrum avoid behavioral drugs in ER
An innovative care model developed by Nemours Children’s Hospital for children with autism spectrum disorders (ASD) in the emergency department (ED) reduces the use of medication administered to kids who are prone to stress and sensory overload in this care setting. Information about this care model was presented today at the Institute for Healthcare Improvement’s […]
New tumor model helps researchers treat pancreatic cancer
Patients diagnosed with pancreatic cancer face a poor prognosis because the tumor forms dense scar-like tissue that is difficult for chemotherapy drugs to penetrate, but a new model may help researchers develop new therapies. “More than 85 percent of pancreatic tumors form this fibrous tissue,” explained Assistant Professor Joshua Reineke of the South Dakota State […]
Model Identifies Adolescents at Risk for Smoking Initiation
THURSDAY, Oct. 18, 2018 — A novel prognostic tool can be used to accurately identify adolescents at risk for initiating cigarette smoking, according to a study published online Oct. 1 in Pediatrics. Marie-Pierre Sylvestre, Ph.D., from the Université de Montréal, and colleagues used data from the Nicotine Dependence in Teens study. A total of 1,294 […]
AI model takes us closer to personalised cancer treatments
The ‘holy grail’ of cancer treatment: Scientists take a huge step towards personalised therapies after developing an AI model that predicts how tumours will respond to drugs Could help doctors identify the best treatment and drug dose for each patient The model may be available on the NHS in as little as 10 years time […]
New model mimics human tumors for accurate testing of cancer drugs
Walter and Eliza Hall Institute researchers have genetically engineered a new laboratory model that enables accurate testing of anti-cancer drugs by mimicking the complexity of human cancers. Using this advanced model, researchers will be able to discover the safest and most effective ways to use promising drugs called MCL-1 inhibitors in the clinic. The work […]
Model estimates mortality in patients waiting for hearts
(HealthDay)—For patients with advanced heart failure who are listed for transplantation, mortality risk is related to adverse events and end-organ dysfunction that vary over time, according to a study published in the Aug. 7 issue of the Journal of the American College of Cardiology. Eugene H. Blackstone, M.D., from the Cleveland Clinic, and colleagues developed […]
Engrafted stem cell-derived lung organoids that model human lung development
Researchers have now grown lung organoids from human embryonic stem cells (hESCs) that, after implantation in mice, can develop mature alveolar type 1 (AT1) and AT2 cells and architecture approximating that of human lungs. The strategy is the first to generate both lung distal progenitor cells and mature AT1-like cells. The study is published in […]
Researchers look to worms for a new model of a peripheral nervous system disease
Studying transthyretin amyloidoses-a group of progressive nerve and cardiac degenerative diseases caused by the buildup of misfolded transthyretin (TTR) proteins in the body-has long been hampered by the lack of animal models of the disease. Mice, for instance, don’t show the same symptoms as humans, even when misfolded TTR accumulates in their organs. Now, scientists […]