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2D NMR Spectroscopy: Fundamentals, Methods and Applications

Nuclear magnetic resonance (NMR) spectroscopy was developed to detect protons, and has since then been applied in studying the molecular structure of proteins, RNA, DNA complexes, and interactions between these molecules. betibup33 | Shutterstock Fundamentals of 2D NMR 2D NMR differs from 1D NMR by the acquisition stage being separated from the excitation stage. The […]

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17O NMR Spectroscopy: Applications, Benefits, and Limitations

NMR makes use of specific stable isotopes, commonly 13C, but there is only one NMR-active stable isotope for oxygen, 17O. The effects of using this oxygen isotope over other isotopes include lower NMR receptivity, a nonzero quadrupole moment, and a larger chemical shift range compared to many other isotopes. Skip to: What are the Applications […]