Korea Brain Research Institute (KBRI, President: Pann-Ghill Suh) announced on February 10 that its research team led by Dr. Ja Wook Koo and Dr. Sukwon Lee proved that the posterior parietal cortex (PPC) of the cerebrum plays a role in fear renewal occurring in a novel context. The posterior parietal cortex (PPC) is a part […]
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Study reveals how drug abstinence changes gene expression, making relapse more likely
A new preclinical study by University at Buffalo researchers reveals the genetic basis of relapse, one of the most detrimental but poorly understood behaviors related to addiction. Craig Werner, Ph.D., is first author on a paper published Oct. 9 in Science Advances that demonstrates how prolonged abstinence after cocaine use drives gene changes that promote […]
Study pinpoints what causes relapse after cancer immunotherapy
Harnessing the body’s immune system to fight off cancer, a tactic known as immunotherapy, has tremendously improved outcomes for patients. But a lingering problem with immunotherapy, as with many other cancer treatments, is relapse. In many cases the tumor comes back, and doctors don’t know why. Now, research from the lab of Elaine Fuchs, Rockefeller’s […]
Women’s hormones play role in drug addiction, higher relapse rates
Women’s hormonal cycles may not only make them more prone to drug addiction but also more affected by triggers that lead to relapse, a new Vanderbilt University study revealed. The findings are especially significant since there are virtually no addiction studies in women that account for these cycles. Erin Calipari, an assistant professor of pharmacology […]
Trial participation among factors influencing risk of relapse in AYA leukemia patients
Adolescent and young adult (AYA) patients with acute lymphoblastic leukemia (ALL) were significantly more likely to relapse than pediatric ALL patients, and factors including lower clinical trial enrollment and shorter duration of therapy were associated with relapse. The study is published in the Cancer Epidemiology, Biomarkers & Prevention, by Julie A. Wolfson, MD, MSHS, assistant […]