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LONG BEACH — On a recent Thursday afternoon, Rhianna Alvarado struggled to don her protective gloves, which were too big for her petite hands. With her mom coaching her every move, she edged close to her father and gently removed the plastic tube from his throat that allows him to breathe. She then cautiously inserted a new […]
Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor’s healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer. While this therapy can be life-saving, a major complication is the development of graft-versus-host disease (GVHD), which causes significant morbidity and can be fatal. Before allogenic […]
The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction and chronic infections. To explore the cellular and molecular mechanisms underlying the role of NKCC1 in the intestinal pathology, Eric Delpire, Ph.D., and […]
Prime Minister Scott Morrison’s declaration of “war” against the COVID-19 pandemic requires a mobilization of all available resources to the front-lines of the response—and this includes a bigger role for our armed forces. So far, the most visible force on our streets has been the police. In NSW, the police are now patrolling supermarkets to […]
Support cells in the nervous system help protect motor neurons in the early-stages of sporadic motor neuron disease, according to new research from the Crick and UCL. Motor neuron disease is a degenerative condition which destroys the nerve cells (motor neurons) in the brain and spinal cord, which control movement, speech, swallowing and breathing. The […]
The ability to create new neurons may exist as built-in protection for sensitive brain areas, according to research in mice recently published in JNeurosci. For a quarter of a century, scientists have known that the brain creates new neurons even into adulthood—a process called adult neurogenesis. The question has been: why? Adult neurogenesis occurs in […]
A Cornell study provides important new insights into a common and deadly type of gastric cancer. Incidence of this cancer, called gastric squamous-columnar junction (SCJ) cancer, also known as gastroesophageal cancer, rose 2.5 times in the United States between the 1970s and 2000s, while cases of all gastric cancers have decreased by more than 80% […]
A study recently published by researchers from the Ohio Musculoskeletal and Neurological Institute (OMNI) at the Ohio University Heritage College of Osteopathic Medicine, in collaboration with a colleague from outside Ohio University, finds new evidence to support the belief that the nervous system plays an important role in age-related weakness. An article published Sept. 25 […]
As health agencies battle to stop the spread of the deadly Ebola virus in eastern DR Congo, some survivors of the disease are playing a crucial role in aiding victims of the worst outbreak in the country’s history. More than 2,100 people have died from Ebola in Democratic Republic of Congo since the haemorrhagic fever […]
The failure of pancreatic beta cells to release appropriate amounts of insulin in response to rising blood glucose levels is a hallmark of type 2 diabetes. During the past decade researchers have shown that microtubules—part of the cell’s cytoskeleton—play an important role in regulating the delivery of insulin granules to the cell membrane for secretion. […]