Results from a pioneering clinical trials programme that delivered an experimental treatment directly to the brain offer hope that it may be possible to restore the cells damaged in Parkinson’s. The multimillion-pound study, funded by Parkinson’s UK with support from The Cure Parkinson’s Trust and in association with the North Bristol NHS Trust, aimed to […]
Mother is symptom-free of cancer after finding her own trial online
‘If I relied on the NHS, I’d already be dead’: Mother battling stage four lung cancer is symptom-free after finding her own trial online when doctors said she could die within six months Heidi Spencer, 45, was offered palliative care from the NHS She went against doctors and found a genetic test online, FoundationOne, It […]
Trial participation among factors influencing risk of relapse in AYA leukemia patients
Adolescent and young adult (AYA) patients with acute lymphoblastic leukemia (ALL) were significantly more likely to relapse than pediatric ALL patients, and factors including lower clinical trial enrollment and shorter duration of therapy were associated with relapse. The study is published in the Cancer Epidemiology, Biomarkers & Prevention, by Julie A. Wolfson, MD, MSHS, assistant […]
Results from the ULTIMATE trial reported
September 24, 2018—The first study designed to determine the benefits of intravascular ultrasound (IVUS) guidance over angiography guidance during drug-eluting stent (DES) implantation in all-comer patients found that IVUS improved clinical outcomes by lowering the rate of target vessel failure at one year. Findings from the ULTIMATE trial were reported today at the 30th annual […]
First HIV immunotherapy drug proves safe in phase 1 trial
First ever HIV immunotherapy drug proves safe in phase 1 trial – paving the way to a cure Scientists at UNC and Children’s National Health System have proved the safety of immunotherapy in HIV patients They are receiving $4m a year for 5 years from GlaxoSmithKline in a bid to arrive at the first HIV cure […]
Clinical trial suggests new direction for heavy-smoking head and neck cancer patients
Patients with a greater than 10 pack/year history of smoking tend to develop an especially dangerous form of head and neck squamous cell cancer (HNSCC) for which prognosis remains poor and treatments have changed little during the past two decades. However, recent phase 1 clinical trial results by the Head and Neck Cancer Group at […]
Alzheimer’s Drug Trial Offers New Hope, But Uncertainty, Too
THURSDAY, July 26 — There have been many setbacks on the long road to finding a treatment that might slow or stop Alzheimer’s disease, but a new trial offers a glimmer of hope. Researchers report that an experimental drug called BAN2401 slowed mental decline by as much as 30 percent in Alzheimer’s patients. It also […]
Alzheimer’s drug trial offers new hope, but uncertainty, too
(HealthDay)—There have been many setbacks on the long road to finding a treatment that might slow or stop Alzheimer’s disease, but a new trial offers a glimmer of hope. Researchers report that an experimental drug called BAN2401 slowed mental decline by as much as 30 percent in Alzheimer’s patients. It also appeared to clear away […]
Cell ‘chatter’ discovery could open clinical trial opportunity for fatal childhood brain tumour
Brain tumours are hard to treat. But even this is a harrowing understatement for some forms of the disease. Diffuse intrinsic pontine glioma (DIPG) is one such example. These rare brain tumours almost exclusively affect children, and they’re invariably fatal. “Almost all children with DIPG sadly die within a couple of years of diagnosis,” says […]