Health News

‘Patchwork’ tumors prevalent across multiple cancer types

Researchers at the Francis Crick Institute, as part of an international collaboration of scientists through the Pan-Cancer Analysis of Whole Genomes Consortium, have analyzed the whole genomes of tumor samples from over 2,600 patients with different types of cancer. They identified a high prevalence of genetic diversity within individual tumors, which they further characterized. Their […]

Health News

Tackling tumors with two types of virus

An international research group led by the University of Basel has developed a promising strategy for therapeutic cancer vaccines. Using two different viruses as vehicles, they administered specific tumor components in experiments on mice with cancer in order to stimulate their immune system to attack the tumor. The approach is now being tested in clinical […]

Health News

A protein that can melt tumors

For the second time, cancer researchers at Vanderbilt have discovered a protein that—when genetically manipulated to impede it from interacting with a gene responsible for cancer genesis—effectively melts tumors in days. The article, “MYC regulates ribosome biogenesis and mitochondrial gene expression programs through interaction with Host Cell Factor-1,” was published in the journal eLife on […]

Health News

Pre-brain surgery test protects language in some tumors

A technique that maps a patient’s language centers before going into surgery works best when their brain tumor is not in those areas. The finding, published by Nagoya University researchers in the journal Scientific Reports, refines understanding of the test’s effectiveness and could help improve surgical planning. Gliomas are a common brain tumor that require […]

Health Problems

Cellular origins of pediatric brain tumors identified

A research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado, of the Research Institute of the McGill University Health Centre (RI-MUHC), and Dr. Michael Taylor, of The Hospital for Sick Children (SickKids), discovered that several types of highly aggressive and, […]

Health Problems

Scientists create brain-mimicking environment to grow 3-D tissue models of brain tumors

A team of Tufts University-led researchers has developed three-dimensional (3-D) human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, a significant advancement for the study of brain tumor biology and pharmacological response. The study was published today in Nature Communications. The researchers created models that include brain-derived extracellular matrix (ECM) […]