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A team of Tufts University-led researchers has developed three-dimensional (3-D) human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, a significant advancement for the study of brain tumor biology and pharmacological response. The study was published today in Nature Communications. The researchers created models that include brain-derived extracellular matrix (ECM) […]
Germ cell tumors constitute a diverse group of rare tumors, which occur in the testes, ovaries and also in other places. Some germ cell tumors exist prenatally, while others present during or after puberty. The majority are benign. Malignant germ cell tumors most frequently appear in the testicle of adolescent and young adult men. Fortunately, […]
Protection mechanism discovered: How the immune system protects against bowel cancer Again and again, it is pointed out how important it is to strengthen its defenses. A healthy immune system can fend off pathogens and diseases preserve. It may even protect against the most serious diseases such as colon cancer. One of the most common […]
Can this revolutionize the fast test, the cancer diagnosis? A new type of blood or tissue test can diagnose within just ten minutes cancer. As the basis of a newly-discovered structure of DNA, which seems to be the case with all types of cancer to occur. The Test detects quickly and easily, whether these structures […]
A new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of treatment even before changes are identified on scans, according to research led by UCSF Benioff Children’s Hospitals and Children’s National Health System. Unlike a standard brain biopsy, which entails drilling […]
Walter and Eliza Hall Institute researchers have genetically engineered a new laboratory model that enables accurate testing of anti-cancer drugs by mimicking the complexity of human cancers. Using this advanced model, researchers will be able to discover the safest and most effective ways to use promising drugs called MCL-1 inhibitors in the clinic. The work […]
UCSF Benioff Children’s Hospitals are harnessing next-generation genomic technology to develop individualized drug cocktails in a new trial for children with a type of malignant brain tumor. This precision-medicine approach offers a new strategy in the treatment for high-grade glioma, an intractable brain cancer in which survival has plateaued for decades. In the trial, UCSF […]
Glioblastoma is a highly aggressive brain cancer that predominantly affects people in their 50s, 60s and 70s. Even under the best available care, half of the patients die within one year after diagnosis, and very few live on for more than three years. Many efforts to develop new, targeted treatments have failed over the last […]
A new technology developed by Purdue University researchers allows different concentrations of a drug or a chemical to be targeted at different areas of the same cancerous tissue in the laboratory. The discovery may help the more than 1.7 million people the National Cancer Institute predicts will be diagnosed with the deadly disease this year […]
Glioblastoma brain tumors can have an unusual effect on the body’s immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body’s defenses. Where the T-cells go has been unclear, even as immunotherapies are increasingly employed to stimulate the body’s natural ability to fight invasive tumors. Now researchers […]